TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
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chr19:16,751,207-18,143,862
Best TWAS P=1.05e-07 · Best GWAS P=3.7e-09 conditioned to 0.000188
16.8M
17M
17.2M
17.4M
17.6M
17.8M
18M
18.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
GTPBP3
0.44
0.05
lasso
9
0.09
2.3e-03
3.7
5.3
1.1e-07
-0.04
0.05
0.08
TRUE
3
The Cancer Genome Atlas
Stomach Adenocarcinoma
HAUS8
0.06
0.04
blup
55
0.04
1.0e-03
-4.6
5.2
1.7e-07
0.60
0.03
0.50
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
HAUS8
0.13
0.10
blup
55
0.11
7.8e-12
-4.6
5.2
2.0e-07
0.73
0.44
0.56
FALSE