[Hub]/) : Traits : Whole body fat-free mass :

chr3:87,404,256-88,911,119

Best TWAS P=6.8e-12 · Best GWAS P=3.26e-12 conditioned to 0.851

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C3orf38 0.08 0.00 enet 14 0.04 2.3e-05 -5.5 -6.6 3.0e-11 0.56 0.06 0.88 FALSE
2 GTEx Adipose Visceral Omentum C3orf38 0.09 0.00 lasso 5 0.00 5.2e-01 -2.4 5.4 5.6e-08 -0.51 0.05 0.28 FALSE
3 GTEx Artery Aorta C3orf38 0.06 0.06 lasso 7 0.05 6.0e-04 -5.7 5.8 8.7e-09 -0.67 0.46 0.33 FALSE
4 GTEx Cells Transformed fibroblasts ZNF654 0.08 0.09 enet 6 0.10 3.1e-08 -6.9 -6.9 6.8e-12 0.57 0.01 0.99 TRUE
5 GTEx Esophagus Mucosa C3orf38 0.11 0.06 lasso 7 0.07 1.5e-05 -5.7 6.4 1.9e-10 -0.67 0.12 0.88 FALSE
6 GTEx Heart Atrial Appendage CGGBP1 0.25 0.15 enet 30 0.16 1.5e-07 -3.4 -5.3 1.3e-07 0.60 0.21 0.62 TRUE
7 GTEx Nerve Tibial C3orf38 0.09 0.05 lasso 4 0.04 6.3e-04 -5.8 5.8 6.4e-09 -0.68 0.48 0.35 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic ZNF654 0.09 0.01 lasso 7 0.06 2.7e-04 -5.8 -5.2 1.7e-07 0.64 0.10 0.24 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic C3orf38 0.09 0.07 lasso 6 0.04 2.8e-03 -5.5 5.4 6.1e-08 -0.68 0.36 0.22 FALSE
10 GTEx Testis C3orf38 0.11 0.01 enet 12 0.00 1.9e-01 -5.2 5.2 1.9e-07 -0.72 0.11 0.24 FALSE
11 GTEx Thyroid C3orf38 0.12 0.08 lasso 18 0.07 1.0e-05 -5.5 5.6 2.3e-08 -0.68 0.87 0.11 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma C3orf38 0.01 0.01 lasso 3 0.01 1.2e-03 -5.6 5.5 4.3e-08 -0.65 0.04 0.25 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C3orf38 0.02 0.01 blup 24 0.02 2.0e-03 -5.6 5.5 2.8e-08 -0.65 0.07 0.19 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf38 0.02 0.03 lasso 1 0.03 1.9e-04 -5.6 5.6 2.1e-08 -0.69 0.05 0.45 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma C3orf38 0.03 0.05 lasso 1 0.05 8.1e-06 -5.6 5.6 2.1e-08 -0.69 0.45 0.42 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma CGGBP1 0.30 0.07 enet 11 0.09 2.3e-09 -7.0 -5.9 4.1e-09 0.80 0.00 1.00 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma ZNF654 0.03 0.04 lasso 3 0.03 4.6e-04 -5.6 -5.7 1.2e-08 0.69 0.16 0.53 FALSE