Best TWAS P=4.3e-10 · Best GWAS P=7.47e-09 conditioned to 3.39e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C1orf54 | 0.06 | 0.02 | enet | 13 | 0.02 | 1.2e-05 | 5.1 | -6.2 | 4.3e-10 | -0.04 | 0.00 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C1orf54 | 0.04 | 0.04 | lasso | 2 | 0.03 | 2.0e-04 | 5.1 | -5.2 | 1.6e-07 | -0.27 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C1orf54 | 0.06 | 0.03 | lasso | 1 | 0.03 | 1.3e-04 | 5.1 | -5.1 | 3.0e-07 | -0.27 | 0.00 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MRPS21 | 0.13 | 0.13 | enet | 10 | 0.13 | 1.7e-14 | -4.1 | 5.5 | 2.9e-08 | 0.21 | 0.06 | 0.88 | FALSE |