Best TWAS P=1.12e-12 · Best GWAS P=4.91e-62 conditioned to 6.2e-56
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | LEMD3 | 0.14 | 0.05 | lasso | 8 | 0.05 | 1.1e-03 | -3.7 | -5.4 | 6.9e-08 | 0.11 | 0.33 | 0.30 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | RBMS1P1 | 0.17 | 0.03 | lasso | 11 | 0.04 | 7.3e-03 | 9.5 | -7.1 | 1.1e-12 | -0.40 | 0.07 | 0.40 | TRUE |
| 3 | GTEx | Nerve Tibial | LEMD3 | 0.12 | 0.14 | enet | 13 | 0.16 | 2.0e-11 | -4.2 | -5.3 | 1.3e-07 | 0.11 | 0.62 | 0.38 | FALSE |