TWAS
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Usage
Models
Genes
Traits
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Traits
:
Basal metabolic rate
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chr15:41,287,689-41,822,302
Best TWAS P=2.47e-08 · Best GWAS P=3.56e-07 conditioned to 0.00718
41.3M
41.4M
41.5M
41.6M
41.7M
41.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
CHP
0.06
0.01
blup
54
0.03
4.7e-04
-2.8
5.6
2.5e-08
-0.49
0.04
0.11
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
CHP
0.21
0.11
lasso
4
0.12
5.1e-13
-5.1
5.2
1.7e-07
-0.92
0.00
1.00
FALSE