TWAS
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Traits
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Traits
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Basal metabolic rate
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chr5:87,006,055-88,677,293
Best TWAS P=2.98e-14 · Best GWAS P=8.02e-17 conditioned to 0.00443
87M
87.2M
87.4M
87.6M
87.8M
88M
88.2M
88.4M
88.6M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
CTC-498M16.2
0.11
0.13
lasso
6
0.12
1.2e-14
-8.2
-7.6
3.0e-14
0.89
0.01
0.99
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
LINC00461
0.10
0.07
lasso
2
0.05
4.5e-07
5.7
5.8
8.3e-09
-0.05
1.00
0.00
TRUE