Best TWAS P=2.98e-14 · Best GWAS P=8.02e-17 conditioned to 0.00443
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 5.7 | 5.8 | 8.3e-09 | -0.05 | 1.00 | 0.00 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -8.2 | -7.6 | 3.0e-14 | 0.89 | 0.01 | 0.99 | TRUE |