TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of leg (left)
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chr7:98,791,892-100,628,107
Best TWAS P=1.3e-09 · Best GWAS P=5.7e-07 conditioned to 0.0101
99M
99.5M
100M
100.5M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells EBV-transformed lymphocytes
LAMTOR4
0.40
0.19
enet
39
0.21
2.2e-07
-4.1
6.1
1.3e-09
-0.44
0.13
0.58
TRUE
1
GTEx
Brain Cerebellar Hemisphere
PMS2P1
0.14
0.02
enet
11
0.06
1.3e-02
-3.8
5.4
5.3e-08
-0.65
0.03
0.34
FALSE
3
GTEx
Vagina
TRIM4
0.32
0.19
lasso
7
0.27
6.0e-07
-4.0
5.1
2.8e-07
-0.57
0.12
0.46
FALSE