TWAS
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Genes
Traits
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Traits
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Impedance of leg (left)
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chr12:45,363,545-47,465,082
Best TWAS P=2.63e-16 · Best GWAS P=1.66e-18 conditioned to 0.000287
45.5M
46M
46.5M
47M
47.5M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SLC38A2
0.10
0.06
blup
30
0.05
0.00083
8.4
-8.2
2.6e-16
-0.86
0.02
0.83
TRUE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
ANO6
0.08
0.00
blup
108
0.02
0.00652
4.2
-5.4
8.3e-08
0.02
0.01
0.15
TRUE
1
METSIM
Adipose
SLC38A2
0.02
0.02
blup
341
0.01
0.00581
7.9
-8.1
5.1e-16
-0.90
0.04
0.93
FALSE
4
The Cancer Genome Atlas
Soft Tissue Sarcoma
SLC38A2
0.06
0.01
blup
30
0.03
0.00513
8.4
-7.6
2.8e-14
-0.92
0.03
0.57
FALSE