Best TWAS P=2.63e-16 · Best GWAS P=1.66e-18 conditioned to 0.000287
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 0.00581 | 7.9 | -8.1 | 5.1e-16 | -0.90 | 0.04 | 0.93 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 0.00083 | 8.4 | -8.2 | 2.6e-16 | -0.86 | 0.02 | 0.83 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ANO6 | 0.08 | 0.00 | blup | 108 | 0.02 | 0.00652 | 4.2 | -5.4 | 8.3e-08 | 0.02 | 0.01 | 0.15 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 0.00513 | 8.4 | -7.6 | 2.8e-14 | -0.92 | 0.03 | 0.57 | FALSE |