Best TWAS P=1.52e-07 · Best GWAS P=6.66e-08 conditioned to 0.0947
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PLK1S1 | 0.07 | 0.08 | enet | 10 | 0.08 | 4.0e-07 | -5.1 | -5.1 | 2.8e-07 | 0.84 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Testis | PLK1S1 | 0.64 | 0.34 | enet | 33 | 0.39 | 1.0e-18 | -4.2 | -5.1 | 3.0e-07 | 0.85 | 0.54 | 0.44 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | PLK1S1 | 0.09 | 0.02 | blup | 64 | 0.05 | 3.1e-03 | -5.4 | -5.2 | 1.5e-07 | 0.87 | 0.02 | 0.63 | TRUE |