Best TWAS P=8.64e-09 · Best GWAS P=7.54e-07 conditioned to 0.0438
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FUT10 | 0.12 | 0.20 | lasso | 11 | 0.21 | 4.2e-25 | 4.4 | 5.3 | 8.8e-08 | 0.62 | 0.03 | 0.92 | FALSE |
2 | GTEx | Breast Mammary Tissue (Female) | FUT10 | 0.18 | 0.13 | lasso | 5 | 0.13 | 9.5e-05 | 4.9 | 5.2 | 1.8e-07 | 0.86 | 0.02 | 0.87 | FALSE |
3 | GTEx | Pancreas | FUT10 | 0.28 | 0.23 | enet | 20 | 0.22 | 1.4e-09 | 4.2 | 5.8 | 8.6e-09 | 0.57 | 0.04 | 0.89 | TRUE |
4 | The Cancer Genome Atlas | Glioblastoma Multiforme | FUT10 | 0.17 | 0.09 | lasso | 6 | 0.10 | 6.3e-04 | 4.2 | 5.3 | 1.2e-07 | 0.70 | 0.03 | 0.69 | FALSE |
5 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | FUT10 | 0.12 | 0.10 | blup | 68 | 0.09 | 2.6e-04 | 4.4 | 5.3 | 1.1e-07 | 0.67 | 0.03 | 0.83 | FALSE |