Best TWAS P=1.53e-07 · Best GWAS P=9.06e-07 conditioned to 0.00148
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | UPF3A | 0.38 | 0.15 | enet | 24 | 0.32 | 3.6e-27 | 3.9 | -5.2 | 2.2e-07 | 0.41 | 0.10 | 0.61 | FALSE |
| 2 | GTEx | Lung | UPF3A | 0.27 | 0.12 | enet | 23 | 0.17 | 3.4e-13 | 3.6 | -5.2 | 1.9e-07 | 0.41 | 0.16 | 0.39 | FALSE |
| 3 | GTEx | Muscle Skeletal | UPF3A | 0.12 | 0.05 | lasso | 4 | 0.07 | 5.4e-07 | 3.6 | -5.2 | 1.5e-07 | 0.37 | 0.03 | 0.66 | TRUE |
| 4 | GTEx | Stomach | UPF3A | 0.20 | 0.00 | enet | 34 | 0.05 | 2.5e-03 | -3.2 | -5.2 | 2.0e-07 | 0.25 | 0.00 | 0.44 | FALSE |