Best TWAS P=5.61e-12 · Best GWAS P=6.69e-16 conditioned to 0.000483
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BTBD7 | 0.04 | 0.04 | lasso | 2 | 0.03 | 1.8e-04 | -5.1 | 5.5 | 3.9e-08 | -0.43 | 0.88 | 0.06 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | BTBD7 | 0.16 | 0.01 | lasso | 8 | 0.04 | 3.6e-04 | -7.1 | 6.9 | 5.6e-12 | -0.58 | 0.11 | 0.87 | TRUE |
| 3 | GTEx | Testis | BTBD7 | 0.19 | 0.00 | enet | 45 | 0.01 | 9.5e-02 | -5.0 | 5.8 | 6.7e-09 | -0.56 | 0.05 | 0.86 | FALSE |
| 4 | NTR | Blood | BTBD7 | 0.02 | 0.03 | lasso | 2 | 0.02 | 6.1e-08 | -5.1 | 5.6 | 2.6e-08 | -0.47 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C14orf142 | 0.11 | 0.04 | enet | 7 | 0.05 | 7.2e-07 | 3.9 | -6.0 | 2.6e-09 | 0.22 | 0.51 | 0.07 | TRUE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | BTBD7 | 0.02 | 0.01 | blup | 72 | 0.02 | 6.8e-03 | -6.9 | 6.8 | 1.5e-11 | -0.80 | 0.01 | 0.88 | FALSE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BTBD7 | 0.11 | 0.03 | blup | 72 | 0.02 | 8.0e-02 | -7.1 | 6.6 | 3.9e-11 | -0.56 | 0.02 | 0.78 | FALSE |