Best TWAS P=2.69e-10 · Best GWAS P=2.21e-10 conditioned to 0.402
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | GGT7 | 0.06 | 0.00 | enet | 7 | 0.02 | 1.9e-02 | -4.9 | 6.2 | 5.1e-10 | -0.36 | 0.06 | 0.74 | TRUE |
2 | GTEx | Cells EBV-transformed lymphocytes | NCOA6 | 0.11 | 0.06 | enet | 15 | 0.06 | 3.9e-03 | 4.9 | -5.1 | 2.9e-07 | 0.42 | 0.07 | 0.72 | FALSE |
3 | GTEx | Thyroid | MYH7B | 0.06 | 0.03 | enet | 15 | 0.06 | 3.6e-05 | 5.1 | 5.1 | 3.0e-07 | -0.35 | 0.04 | 0.95 | FALSE |
4 | YFS | Blood | EIF2S2 | 0.07 | 0.07 | enet | 25 | 0.06 | 4.3e-20 | -6.0 | 6.3 | 2.7e-10 | -0.88 | 0.02 | 0.98 | TRUE |