Best TWAS P=1.01e-07 · Best GWAS P=1.34e-07 conditioned to 0.194
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | MCM6 | 0.18 | 0.15 | enet | 20 | 0.20 | 8.5e-64 | -5.3 | -5.3 | 1.0e-07 | 0.87 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LCT | 0.04 | 0.02 | blup | 36 | 0.02 | 1.9e-03 | -4.5 | 5.2 | 1.7e-07 | -0.97 | 0.01 | 0.96 | FALSE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | LCT | 0.09 | 0.04 | blup | 36 | 0.05 | 4.9e-04 | -5.3 | 5.2 | 2.2e-07 | -0.89 | 0.00 | 0.84 | FALSE |