[Hub]/) : Traits : Leg fat mass (right) : ← →

chr2:171,867,383-173,555,880

Best TWAS P=3.59e-08 · Best GWAS P=1.15e-08 conditioned to 0.0148

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts DYNC1I2 0.12 0.14 lasso 3 0.14 1.4e-10 -5.3 5.3 1.1e-07 -0.75 0.04 0.96 FALSE
2 GTEx Muscle Skeletal DYNC1I2 0.11 0.12 lasso 2 0.12 6.5e-12 -5.4 5.5 4.6e-08 -0.76 0.04 0.96 FALSE
3 GTEx Skin Sun Exposed Lower leg DYNC1I2 0.11 0.16 lasso 1 0.15 8.9e-13 -5.3 5.3 1.2e-07 -0.75 0.05 0.95 FALSE
4 GTEx Testis DYNC1I2 0.13 0.02 lasso 4 0.01 1.1e-01 -5.5 5.4 5.5e-08 -0.75 0.04 0.77 FALSE
5 ROSMAP Brain Pre-frontal Cortex AC068039.4 0.43 0.64 enet 35 0.65 1.6e-110 -5.3 -5.5 3.6e-08 0.74 0.04 0.96 TRUE
6 YFS Blood SLC25A12 0.09 0.15 lasso 7 0.15 1.3e-45 -5.3 -5.3 1.1e-07 0.73 0.04 0.96 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma DYNC1I2 0.02 0.00 blup 45 0.00 3.6e-02 -5.3 5.4 5.4e-08 -0.70 0.01 0.64 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MAP1D 0.03 0.03 lasso 2 0.02 1.5e-03 -5.3 5.4 7.3e-08 -0.87 0.01 0.94 FALSE