[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr7:71,935,903-73,738,067

Best TWAS P=2.24e-11 · Best GWAS P=3.09e-11 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	METSIM	Adipose	MLXIPL	0.12	0.14	lasso	4	0.13	1.8e-19	6.6	6.7	2.2e-11	0.96	0.01	0.99	TRUE
9	GTEx	Thyroid	MLXIPL	0.23	0.14	lasso	7	0.15	2.1e-11	5.6	6.6	3.5e-11	0.89	0.02	0.98	FALSE
12	The Cancer Genome Atlas	Lung Adenocarcinoma	MLXIPL	0.04	0.03	lasso	1	0.02	2.3e-03	6.6	6.6	3.6e-11	0.99	0.00	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	MLXIPL	0.13	0.06	enet	6	0.09	2.2e-07	6.3	6.6	4.7e-11	0.93	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	MLXIPL	0.06	0.05	lasso	2	0.05	5.1e-10	6.6	6.4	1.4e-10	0.99	0.00	1.00	FALSE
6	GTEx	Skin Sun Exposed Lower leg	MLXIPL	0.12	0.09	lasso	4	0.06	6.1e-06	6.3	6.3	2.6e-10	0.83	0.05	0.95	FALSE
2	GTEx	Adipose Visceral Omentum	MLXIPL	0.16	0.02	lasso	3	0.03	7.8e-03	5.7	6.2	4.0e-10	0.81	0.10	0.88	FALSE
1	GTEx	Adipose Subcutaneous	MLXIPL	0.11	0.07	enet	16	0.07	1.6e-06	5.6	6.2	4.2e-10	0.85	0.04	0.96	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	MLXIPL	0.11	0.11	lasso	3	0.06	2.7e-04	6.3	6.1	8.4e-10	0.75	0.02	0.96	FALSE
7	GTEx	Spleen	NCF1B	0.22	0.10	enet	9	0.08	5.1e-03	5.9	-6.0	1.6e-09	-0.88	0.02	0.67	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	MLXIPL	0.08	0.05	enet	4	0.05	5.3e-06	6.6	5.7	1.2e-08	0.94	0.00	1.00	FALSE
8	GTEx	Testis	MLXIPL	0.10	0.00	lasso	3	0.00	3.3e-01	4.2	5.6	2.1e-08	0.74	0.02	0.59	FALSE
3	GTEx	Adipose Visceral Omentum	NSUN5	0.07	0.03	enet	11	0.04	4.0e-03	6.6	5.3	1.1e-07	0.74	0.02	0.80	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	BCL7B	0.05	0.01	blup	5	0.03	1.3e-03	6.6	-5.1	2.7e-07	-0.60	0.00	0.63	FALSE