[Hub]/) : Traits : Leg fat-free mass (right) :

chr7:134,650,544-136,094,817

Best TWAS P=9.47e-09 · Best GWAS P=1.39e-08 conditioned to 0.0547

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous C7orf73 0.23 0.14 lasso 7 0.18 9.5e-15 4.2 -5.3 9.1e-08 0.70 0.18 0.81 FALSE
2 GTEx Artery Coronary C7orf73 0.40 0.29 enet 18 0.30 1.3e-10 4.2 -5.3 9.4e-08 0.65 0.11 0.88 FALSE
3 GTEx Breast Mammary Tissue C7orf73 0.15 0.11 lasso 6 0.15 4.3e-08 4.1 -5.5 3.2e-08 0.69 0.05 0.94 FALSE
4 GTEx Breast Mammary Tissue (Male) C7orf73 0.24 0.08 lasso 8 0.14 3.5e-04 -5.7 -5.2 1.6e-07 0.81 0.01 0.79 FALSE
5 GTEx Esophagus Mucosa C7orf73 0.42 0.31 lasso 6 0.38 1.3e-26 4.3 -5.4 6.5e-08 0.65 0.53 0.43 FALSE
6 GTEx Nerve Tibial C7orf73 0.19 0.10 lasso 9 0.18 9.5e-13 4.1 -5.7 9.5e-09 0.78 0.02 0.98 TRUE
7 GTEx Skin Not Sun Exposed Suprapubic C7orf73 0.38 0.33 lasso 5 0.37 2.3e-21 4.1 -5.2 2.6e-07 0.61 0.55 0.41 FALSE
8 GTEx Skin Sun Exposed Lower leg C7orf73 0.29 0.28 enet 21 0.32 3.2e-27 4.1 -5.1 2.8e-07 0.58 0.60 0.36 FALSE
9 NTR Blood SLC13A4 0.02 0.01 bslmm 490 0.01 1.6e-03 4.3 5.4 5.2e-08 -0.42 0.13 0.35 FALSE