Best TWAS P=6.64e-09 · Best GWAS P=1.49e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | ZNF605 | 0.23 | 0.07 | lasso | 9 | 0.06 | 4.5e-03 | 5.7 | 5.2 | 1.9e-07 | 0.96 | 0.01 | 0.95 | FALSE |
| 2 | GTEx | Testis | EP400NL | 0.37 | 0.30 | lasso | 5 | 0.36 | 6.0e-17 | 5.4 | -5.8 | 6.6e-09 | 0.02 | 0.01 | 0.99 | TRUE |
| 3 | YFS | Blood | EP400 | 0.06 | 0.08 | lasso | 7 | 0.08 | 5.4e-24 | 5.4 | -5.3 | 1.1e-07 | 0.02 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ANKLE2 | 0.04 | 0.02 | lasso | 2 | 0.02 | 5.8e-06 | 5.6 | 5.3 | 1.0e-07 | 0.96 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | DDX51 | 0.05 | 0.04 | lasso | 2 | 0.05 | 8.1e-04 | 5.2 | 5.4 | 5.5e-08 | 0.00 | 0.03 | 0.84 | FALSE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | DDX51 | 0.05 | 0.03 | blup | 42 | 0.03 | 4.2e-03 | 4.5 | 5.3 | 8.6e-08 | -0.01 | 0.05 | 0.88 | FALSE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | EP400NL | 0.11 | 0.12 | blup | 60 | 0.06 | 2.8e-03 | 4.5 | -5.1 | 2.8e-07 | 0.00 | 0.06 | 0.58 | FALSE |