[Hub]/) : Traits : Leg fat-free mass (right) :

chr12:131,734,725-133,778,796

Best TWAS P=6.64e-09 · Best GWAS P=1.49e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland ZNF605 0.23 0.07 lasso 9 0.06 4.5e-03 5.7 5.2 1.9e-07 0.96 0.01 0.95 FALSE
2 GTEx Testis EP400NL 0.37 0.30 lasso 5 0.36 6.0e-17 5.4 -5.8 6.6e-09 0.02 0.01 0.99 TRUE
3 YFS Blood EP400 0.06 0.08 lasso 7 0.08 5.4e-24 5.4 -5.3 1.1e-07 0.02 0.01 0.99 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma ANKLE2 0.04 0.02 lasso 2 0.02 5.8e-06 5.6 5.3 1.0e-07 0.96 0.00 1.00 TRUE
5 The Cancer Genome Atlas Colon Adenocarcinoma DDX51 0.05 0.04 lasso 2 0.05 8.1e-04 5.2 5.4 5.5e-08 0.00 0.03 0.84 FALSE
6 The Cancer Genome Atlas Soft Tissue Sarcoma DDX51 0.05 0.03 blup 42 0.03 4.2e-03 4.5 5.3 8.6e-08 -0.01 0.05 0.88 FALSE
7 The Cancer Genome Atlas Testicular Germ Cell Tumors EP400NL 0.11 0.12 blup 60 0.06 2.8e-03 4.5 -5.1 2.8e-07 0.00 0.06 0.58 FALSE