[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr20:20,407,782-21,919,054

Best TWAS P=2.79e-10 · Best GWAS P=1.83e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLK1S1 0.08 0.01 lasso 3 0.04 1.1e-05 5.9 5.2 1.5e-07 0.82 0.02 0.98 FALSE
2 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 6.6 6.3 2.8e-10 0.97 0.01 0.99 TRUE
3 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 6.2 5.4 5.2e-08 0.93 0.06 0.94 FALSE
4 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 5.0 5.8 6.9e-09 0.79 0.69 0.31 FALSE
5 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 5.0 5.6 2.2e-08 0.89 0.07 0.93 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 4.9 5.4 6.7e-08 0.88 0.15 0.85 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 5.0 6.0 1.5e-09 0.88 0.12 0.88 FALSE
8 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 5.9 6.2 5.6e-10 0.78 0.03 0.53 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 5.0 5.5 3.6e-08 0.80 0.88 0.12 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 5.0 5.3 1.4e-07 0.85 0.15 0.60 FALSE