Best TWAS P=2.23e-08 · Best GWAS P=2.54e-07 conditioned to 0.0218
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | AC006547.14 | 0.09 | 0.00 | lasso | 4 | 0.00 | 6.9e-01 | 4.4 | -5.2 | 2.5e-07 | 0.55 | 0.03 | 0.23 | FALSE |
2 | GTEx | Thyroid | ARVCF | 0.25 | 0.09 | enet | 39 | 0.20 | 7.5e-15 | 4.4 | 5.6 | 2.2e-08 | -0.59 | 0.08 | 0.87 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARVCF | 0.03 | 0.01 | blup | 116 | 0.01 | 1.1e-02 | -3.8 | -5.2 | 2.1e-07 | 0.58 | 0.01 | 0.30 | FALSE |