[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr7:71,935,903-73,789,730

Best TWAS P=2.45e-11 · Best GWAS P=3.43e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC30 0.13 0.07 enet 32 0.07 2.7e-09 4.6 5.1 2.9e-07 0.30 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous MLXIPL 0.11 0.07 enet 16 0.07 1.6e-06 5.6 6.2 4.5e-10 0.85 0.04 0.96 FALSE
3 GTEx Adipose Visceral Omentum MLXIPL 0.16 0.02 lasso 3 0.03 7.8e-03 5.6 6.2 4.1e-10 0.81 0.10 0.88 FALSE
4 GTEx Adipose Visceral Omentum NSUN5 0.07 0.03 enet 11 0.04 4.0e-03 6.6 5.3 1.1e-07 0.74 0.02 0.80 FALSE
5 GTEx Cells Transformed fibroblasts MLXIPL 0.13 0.06 enet 6 0.09 2.2e-07 6.3 6.6 5.1e-11 0.93 0.01 0.99 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic MLXIPL 0.11 0.11 lasso 3 0.06 2.7e-04 6.3 6.1 8.8e-10 0.75 0.02 0.96 FALSE
7 GTEx Skin Sun Exposed Lower leg MLXIPL 0.12 0.09 lasso 4 0.06 6.1e-06 6.3 6.3 2.8e-10 0.83 0.05 0.95 FALSE
8 GTEx Spleen NCF1B 0.22 0.10 enet 9 0.08 5.1e-03 5.9 -6.0 1.4e-09 -0.88 0.02 0.67 FALSE
9 GTEx Testis MLXIPL 0.10 0.00 lasso 3 0.00 3.3e-01 4.2 5.6 1.9e-08 0.74 0.02 0.59 FALSE
10 GTEx Thyroid MLXIPL 0.23 0.14 lasso 7 0.15 2.1e-11 5.6 6.6 3.7e-11 0.89 0.02 0.98 FALSE
11 METSIM Adipose MLXIPL 0.12 0.14 lasso 4 0.13 1.8e-19 6.6 6.7 2.4e-11 0.96 0.01 0.99 TRUE
12 The Cancer Genome Atlas Breast Invasive Carcinoma MLXIPL 0.06 0.05 lasso 2 0.05 5.1e-10 6.6 6.4 1.6e-10 0.99 0.00 1.00 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma MLXIPL 0.04 0.03 lasso 1 0.02 2.3e-03 6.6 6.6 4.0e-11 0.99 0.00 0.98 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma MLXIPL 0.08 0.05 enet 4 0.05 5.3e-06 6.6 5.7 1.3e-08 0.94 0.00 1.00 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma BCL7B 0.05 0.01 blup 5 0.03 1.3e-03 6.6 -5.1 2.8e-07 -0.60 0.00 0.63 FALSE