Best TWAS P=2.62e-10 · Best GWAS P=1.4e-13 conditioned to 5.95e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RAD52 | 0.14 | 0.07 | lasso | 3 | 0.10 | 1.1e-05 | -5.2 | -6.3 | 2.6e-10 | -0.44 | 0.42 | 0.51 | TRUE |
2 | GTEx | Artery Tibial | B4GALNT3 | 0.49 | 0.24 | enet | 24 | 0.34 | 6.5e-28 | 4.4 | -5.1 | 2.8e-07 | -0.02 | 1.00 | 0.00 | TRUE |
3 | The Cancer Genome Atlas | Esophageal Carcinoma | RAD52 | 0.25 | 0.13 | blup | 66 | 0.19 | 1.1e-06 | 6.8 | -5.8 | 5.6e-09 | -0.61 | 0.00 | 0.99 | FALSE |