[Hub]/) : Traits : Leg predicted mass (right) :

chr4:151,347,355-153,373,680

Best TWAS P=3.34e-12 · Best GWAS P=5.9e-10 conditioned to 0.638

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM160A1 0.04 0.04 blup 436 0.06 1.8e-07 -3.6 5.7 1.1e-08 0.78 0.73 0.27 FALSE
2 GTEx Brain Cerebellar Hemisphere SH3D19 0.28 0.22 lasso 5 0.20 9.3e-06 6.2 -6.1 1.3e-09 -0.98 0.02 0.97 FALSE
3 GTEx Brain Cerebellar Hemisphere RP11-164P12.3 0.19 0.05 enet 20 0.02 8.8e-02 6.2 5.6 2.6e-08 0.83 0.02 0.92 FALSE
4 GTEx Brain Cerebellar Hemisphere RP11-164P12.4 0.47 0.44 enet 18 0.35 6.6e-10 6.1 6.2 6.7e-10 1.00 0.02 0.98 FALSE
5 GTEx Colon Sigmoid PET112 0.13 0.08 enet 18 0.03 2.6e-02 -3.7 5.7 1.0e-08 0.66 0.20 0.55 FALSE
6 GTEx Spleen RP11-164P12.4 0.36 0.26 lasso 10 0.20 5.8e-06 6.2 6.2 6.1e-10 1.00 0.02 0.97 FALSE
7 NTR Blood FAM160A1 0.03 0.02 enet 26 0.02 1.4e-07 -6.0 7.0 3.3e-12 0.92 0.03 0.97 TRUE
8 The Cancer Genome Atlas Breast Invasive Carcinoma FAM160A1 0.04 0.02 blup 99 0.02 1.2e-05 6.2 6.3 3.9e-10 0.92 0.02 0.97 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma FAM160A1 0.06 0.05 lasso 3 0.04 1.8e-03 -6.0 5.7 9.6e-09 0.85 0.04 0.75 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma FAM160A1 0.08 0.05 blup 99 0.05 2.9e-03 -4.1 5.6 1.9e-08 0.92 0.04 0.72 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma FAM160A1 0.09 0.10 lasso 2 0.10 3.3e-10 5.9 6.0 2.2e-09 0.93 0.03 0.97 FALSE
12 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma FAM160A1 0.16 0.14 enet 33 0.11 6.6e-04 6.1 5.8 6.9e-09 0.98 0.03 0.97 FALSE