Best TWAS P=5.69e-08 · Best GWAS P=6.81e-08 conditioned to 0.43
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | BTD | 0.07 | 0.09 | lasso | 3 | 0.07 | 1.2e-09 | 5.3 | 5.4 | 5.7e-08 | 0.95 | 0 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BTD | 0.04 | 0.02 | lasso | 3 | 0.02 | 6.5e-03 | 5.4 | 5.4 | 5.7e-08 | 0.97 | 0 | 0.85 | FALSE |