[Hub]/) : Traits : Leg fat percentage (left) :

chr9:115,320,787-116,752,771

Best TWAS P=8.54e-08 · Best GWAS P=1.95e-07 conditioned to 0.664

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland PRPF4 0.28 0.26 lasso 5 0.21 4.2e-08 5.2 5.2 1.9e-07 0.99 0.00 1.00 FALSE
2 GTEx Breast Mammary Tissue PRPF4 0.27 0.22 lasso 3 0.20 1.2e-10 5.1 5.2 1.6e-07 0.97 0.00 1.00 FALSE
3 GTEx Breast Mammary Tissue (Female) PRPF4 0.12 0.04 lasso 1 0.01 1.9e-01 5.1 5.1 2.7e-07 0.98 0.01 0.79 FALSE
4 GTEx Colon Transverse PRPF4 0.22 0.20 lasso 2 0.17 2.3e-08 5.2 5.2 2.0e-07 1.00 0.00 1.00 FALSE
5 GTEx Esophagus Mucosa PRPF4 0.15 0.18 lasso 2 0.17 3.1e-11 5.1 5.2 2.6e-07 0.98 0.00 1.00 FALSE
6 GTEx Esophagus Muscularis PRPF4 0.20 0.13 enet 7 0.13 1.6e-08 5.1 5.2 1.7e-07 0.97 0.00 1.00 FALSE
7 GTEx Liver PRPF4 0.29 0.14 lasso 7 0.12 4.0e-04 5.1 5.2 1.5e-07 0.93 0.01 0.99 FALSE
8 GTEx Nerve Tibial PRPF4 0.21 0.21 lasso 3 0.23 1.4e-16 5.2 5.2 2.3e-07 1.00 0.00 1.00 FALSE
9 GTEx Pancreas PRPF4 0.38 0.39 lasso 6 0.36 2.6e-16 5.1 5.1 2.8e-07 0.98 0.00 1.00 FALSE
10 GTEx Small Intestine Terminal Ileum PRPF4 0.50 0.30 enet 14 0.33 2.9e-08 5.2 5.4 8.5e-08 0.94 0.00 0.99 TRUE
11 GTEx Stomach PRPF4 0.47 0.40 lasso 4 0.39 5.8e-20 5.1 5.2 2.0e-07 1.00 0.00 1.00 FALSE
12 GTEx Testis PRPF4 0.33 0.17 enet 7 0.18 1.8e-08 5.1 5.2 1.7e-07 0.99 0.00 1.00 FALSE
13 GTEx Thyroid PRPF4 0.53 0.51 lasso 6 0.52 1.9e-46 5.1 5.2 2.6e-07 0.98 0.00 1.00 FALSE
14 YFS Blood CDC26 0.07 0.09 lasso 8 0.09 3.9e-27 5.1 -5.1 2.7e-07 -0.97 0.00 0.99 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRPF4 0.10 0.07 lasso 6 0.07 7.2e-05 5.2 5.2 2.0e-07 0.99 0.00 0.99 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma PRPF4 0.09 0.13 lasso 3 0.12 3.5e-12 5.1 5.2 2.2e-07 0.99 0.00 1.00 FALSE