Best TWAS P=2.84e-08 · Best GWAS P=3.54e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | LHPP | 0.41 | 0.03 | enet | 34 | 0.11 | 4.1e-04 | 3.4 | 5.5 | 2.8e-08 | -0.37 | 0.16 | 0.13 | TRUE |
| 2 | GTEx | Thyroid | METTL10 | 0.19 | 0.09 | enet | 33 | 0.10 | 3.0e-08 | -5.0 | -5.1 | 2.8e-07 | 0.84 | 0.01 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | METTL10 | 0.09 | 0.08 | blup | 43 | 0.11 | 1.2e-09 | -5.1 | -5.2 | 2.6e-07 | 0.96 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | METTL10 | 0.10 | 0.14 | blup | 43 | 0.14 | 7.4e-16 | -5.1 | -5.2 | 2.3e-07 | 0.98 | 0.01 | 0.99 | TRUE |