Best TWAS P=1.01e-07 · Best GWAS P=2.56e-08 conditioned to 0.00729
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | SNX19 | 0.32 | 0.04 | lasso | 5 | 0.13 | 7.4e-04 | 4.4 | -5.3 | 1.0e-07 | 0.67 | 0.09 | 0.82 | TRUE |
| 2 | GTEx | Esophagus Muscularis | SNX19 | 0.31 | 0.18 | enet | 23 | 0.25 | 1.2e-15 | 4.2 | -5.2 | 1.8e-07 | 0.76 | 0.40 | 0.58 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SNX19 | 0.06 | 0.04 | blup | 100 | 0.06 | 1.3e-03 | 4.0 | -5.2 | 2.5e-07 | 0.76 | 0.04 | 0.58 | FALSE |