TWAS
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Traits
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Traits
:
Leg fat mass (left)
:
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chr14:102,544,860-104,074,810
Best TWAS P=1.09e-12 · Best GWAS P=1.93e-17 conditioned to 2.69e-06
102.6M
102.8M
103M
103.2M
103.4M
103.6M
103.8M
104M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
TRAF3
0.04
0.02
enet
7
0.04
4.5e-06
6.7
7.1
1.1e-12
0.79
0.04
0.95
TRUE
1
GTEx
Thyroid
TRAF3
0.10
0.00
enet
20
0.05
1.4e-04
1.0
5.6
2.1e-08
0.59
0.03
0.86
FALSE