Best TWAS P=3.96e-08 · Best GWAS P=2.68e-07 conditioned to 0.0368
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | EDEM3 | 0.19 | 0.14 | enet | 12 | 0.15 | 9.6e-09 | 5.1 | -5.1 | 2.9e-07 | -0.98 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | EDEM3 | 0.14 | 0.07 | lasso | 7 | 0.08 | 4.6e-05 | 5.1 | -5.3 | 8.9e-08 | -0.89 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Thyroid | EDEM3 | 0.11 | 0.07 | enet | 9 | 0.07 | 6.2e-06 | -4.4 | -5.1 | 2.9e-07 | -0.95 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Uterus | EDEM3 | 0.27 | 0.02 | enet | 20 | 0.13 | 1.6e-03 | -3.6 | -5.5 | 4.0e-08 | -0.65 | 0.05 | 0.56 | TRUE |