[Hub]/) : Traits : Leg fat mass (left) : ← →

chr2:171,867,383-173,555,880

Best TWAS P=5.64e-09 · Best GWAS P=7.43e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DYNC1I2 0.13 0.11 enet 13 0.11 4.1e-09 -5.4 5.2 2.3e-07 -0.93 0.03 0.97 FALSE
2 GTEx Artery Aorta SLC25A12 0.13 0.03 lasso 16 0.01 1.2e-01 -5.2 -5.2 2.4e-07 0.94 0.04 0.94 FALSE
3 GTEx Brain Cerebellar Hemisphere DYNC1I2 0.32 0.24 lasso 7 0.26 2.0e-07 -4.8 5.2 2.2e-07 -0.91 0.04 0.96 FALSE
4 GTEx Cells Transformed fibroblasts DYNC1I2 0.12 0.14 lasso 3 0.14 1.4e-10 -5.6 5.6 2.0e-08 -0.98 0.03 0.97 FALSE
5 GTEx Muscle Skeletal DYNC1I2 0.11 0.12 lasso 2 0.12 6.5e-12 -5.7 5.8 8.3e-09 -0.97 0.03 0.97 FALSE
6 GTEx Skin Sun Exposed Lower leg DYNC1I2 0.11 0.16 lasso 1 0.15 8.9e-13 -5.6 5.6 2.3e-08 -0.98 0.03 0.97 FALSE
7 GTEx Testis DYNC1I2 0.13 0.02 lasso 4 0.01 1.1e-01 -5.8 5.7 1.1e-08 -0.96 0.03 0.82 FALSE
8 ROSMAP Brain Pre-frontal Cortex SLC25A12 0.13 0.08 lasso 6 0.11 1.8e-13 -5.6 -5.1 2.9e-07 0.90 0.03 0.97 FALSE
9 ROSMAP Brain Pre-frontal Cortex AC068039.4 0.43 0.64 enet 35 0.65 1.6e-110 -5.6 -5.8 5.6e-09 0.97 0.03 0.97 TRUE
10 YFS Blood SLC25A12 0.09 0.15 lasso 7 0.15 1.3e-45 -5.6 -5.6 1.8e-08 0.97 0.03 0.97 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma DYNC1I2 0.02 0.00 blup 45 0.00 3.6e-02 -5.6 5.5 2.8e-08 -0.77 0.01 0.68 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DYNC1I2 0.05 0.06 lasso 4 0.05 6.3e-06 -5.8 5.3 8.9e-08 -0.99 0.01 0.99 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MAP1D 0.03 0.03 lasso 2 0.02 1.5e-03 -5.4 5.4 6.2e-08 -0.74 0.01 0.93 FALSE