[Hub]/) : Traits : Leg fat mass (left) : ← →

chr2:171,867,383-173,555,880

Best TWAS P=5.64e-09 · Best GWAS P=7.43e-09 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	ROSMAP	Brain Pre-frontal Cortex	AC068039.4	0.43	0.64	enet	35	0.65	1.6e-110	-5.6	-5.8	5.6e-09	0.97	0.03	0.97	TRUE
5	GTEx	Muscle Skeletal	DYNC1I2	0.11	0.12	lasso	2	0.12	6.5e-12	-5.7	5.8	8.3e-09	-0.97	0.03	0.97	FALSE
7	GTEx	Testis	DYNC1I2	0.13	0.02	lasso	4	0.01	1.1e-01	-5.8	5.7	1.1e-08	-0.96	0.03	0.82	FALSE
10	YFS	Blood	SLC25A12	0.09	0.15	lasso	7	0.15	1.3e-45	-5.6	-5.6	1.8e-08	0.97	0.03	0.97	FALSE
4	GTEx	Cells Transformed fibroblasts	DYNC1I2	0.12	0.14	lasso	3	0.14	1.4e-10	-5.6	5.6	2.0e-08	-0.98	0.03	0.97	FALSE
6	GTEx	Skin Sun Exposed Lower leg	DYNC1I2	0.11	0.16	lasso	1	0.15	8.9e-13	-5.6	5.6	2.3e-08	-0.98	0.03	0.97	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	DYNC1I2	0.02	0.00	blup	45	0.00	3.6e-02	-5.6	5.5	2.8e-08	-0.77	0.01	0.68	FALSE
13	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MAP1D	0.03	0.03	lasso	2	0.02	1.5e-03	-5.4	5.4	6.2e-08	-0.74	0.01	0.93	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DYNC1I2	0.05	0.06	lasso	4	0.05	6.3e-06	-5.8	5.3	8.9e-08	-0.99	0.01	0.99	FALSE
3	GTEx	Brain Cerebellar Hemisphere	DYNC1I2	0.32	0.24	lasso	7	0.26	2.0e-07	-4.8	5.2	2.2e-07	-0.91	0.04	0.96	FALSE
1	GTEx	Adipose Subcutaneous	DYNC1I2	0.13	0.11	enet	13	0.11	4.1e-09	-5.4	5.2	2.3e-07	-0.93	0.03	0.97	FALSE
2	GTEx	Artery Aorta	SLC25A12	0.13	0.03	lasso	16	0.01	1.2e-01	-5.2	-5.2	2.4e-07	0.94	0.04	0.94	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	SLC25A12	0.13	0.08	lasso	6	0.11	1.8e-13	-5.6	-5.1	2.9e-07	0.90	0.03	0.97	FALSE