TWAS
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
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chr3:14,947,539-16,612,886
Best TWAS P=6.68e-08 · Best GWAS P=1.64e-07 conditioned to 0.354
15M
15.2M
15.4M
15.6M
15.8M
16M
16.2M
16.4M
16.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
AC090945.1
0.10
0.12
lasso
7
0.11
2.8e-14
5.0
5.4
6.7e-08
0.89
0.04
0.96
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
BTD
0.04
0.02
lasso
3
0.02
6.5e-03
5.2
5.4
7.8e-08
0.86
0.01
0.78
FALSE
1
ROSMAP
Brain Pre-frontal Cortex
BTD
0.07
0.09
lasso
3
0.07
1.2e-09
5.2
5.3
1.1e-07
0.78
0.01
0.99
FALSE