[Hub]/) : Traits : Leg fat mass (left) : ← →

chr3:87,495,550-88,911,119

Best TWAS P=5.11e-11 · Best GWAS P=1.05e-10 conditioned to 0.00295

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C3orf38	0.08	0.00	enet	14	0.04	2.3e-05	-6.1	-6.6	5.1e-11	0.63	0.05	0.90	TRUE
6	GTEx	Esophagus Mucosa	C3orf38	0.11	0.06	lasso	7	0.07	1.5e-05	-6.1	6.5	7.1e-11	-0.91	0.06	0.93	FALSE
5	GTEx	Cells Transformed fibroblasts	ZNF654	0.08	0.09	enet	6	0.10	3.1e-08	-6.4	-6.5	8.4e-11	0.99	0.01	0.99	FALSE
3	GTEx	Artery Aorta	C3orf38	0.06	0.06	lasso	7	0.05	6.0e-04	-6.2	6.2	5.1e-10	-0.80	0.07	0.90	FALSE
7	GTEx	Nerve Tibial	C3orf38	0.09	0.05	lasso	4	0.04	6.3e-04	-6.2	6.2	5.1e-10	-0.80	0.07	0.90	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF654	0.03	0.04	lasso	3	0.03	4.6e-04	-6.2	-6.2	5.1e-10	0.80	0.02	0.93	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf38	0.02	0.03	lasso	1	0.03	1.9e-04	-6.2	6.2	6.8e-10	-0.79	0.02	0.76	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	C3orf38	0.03	0.05	lasso	1	0.05	8.1e-06	-6.2	6.2	6.8e-10	-0.79	0.03	0.96	FALSE
11	GTEx	Thyroid	C3orf38	0.12	0.08	lasso	18	0.07	1.0e-05	-6.1	6.1	9.8e-10	-0.80	0.08	0.92	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	C3orf38	0.09	0.07	lasso	6	0.04	2.8e-03	-6.1	6.1	1.2e-09	-0.78	0.08	0.84	FALSE
10	GTEx	Testis	C3orf38	0.11	0.01	enet	12	0.00	1.9e-01	-6.0	6.0	1.6e-09	-0.42	0.08	0.43	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	C3orf38	0.01	0.01	lasso	3	0.01	1.2e-03	-6.1	6.0	2.1e-09	-0.80	0.02	0.64	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C3orf38	0.02	0.01	blup	24	0.02	2.0e-03	-6.1	6.0	2.4e-09	-0.82	0.02	0.71	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	ZNF654	0.09	0.01	lasso	7	0.06	2.7e-04	-6.2	-5.8	5.5e-09	0.74	0.05	0.61	FALSE
12	GTEx	Uterus	ZNF654	0.29	-0.01	lasso	4	0.01	1.7e-01	-6.2	-5.7	1.2e-08	0.71	0.05	0.54	FALSE
4	GTEx	Artery Tibial	C3orf38	0.11	0.03	lasso	6	0.04	3.7e-04	-6.1	5.5	3.8e-08	-0.70	0.08	0.85	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	C3orf38	0.05	0.05	blup	24	0.05	1.1e-05	-6.2	5.3	1.1e-07	-0.76	0.03	0.96	FALSE
2	GTEx	Adipose Visceral Omentum	C3orf38	0.09	0.00	lasso	5	0.00	5.2e-01	-2.3	5.3	1.3e-07	-0.72	0.04	0.34	FALSE