Best TWAS P=9.12e-18 · Best GWAS P=9.15e-19 conditioned to 7.34e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 8.5 | 8.6 | 9.1e-18 | 0.95 | 0.02 | 0.98 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -8.4 | -7.8 | 4.9e-15 | 0.13 | 0.07 | 0.93 | TRUE |