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Traits
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Leg fat-free mass (left)
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chr7:49,817,957-51,215,365
Best TWAS P=3.79e-10 · Best GWAS P=1.68e-12 conditioned to 1.59e-06
49.8M
50M
50.2M
50.4M
50.6M
50.8M
51M
51.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Small Intestine Terminal Ileum
FIGNL1
0.21
0.23
lasso
4
0.22
1.3e-05
-6.8
-6.3
3.8e-10
-0.44
0.07
0.75
TRUE
3
The Cancer Genome Atlas
Stomach Adenocarcinoma
FIGNL1
0.05
0.00
blup
68
0.01
5.4e-02
-6.7
-5.2
2.4e-07
-0.18
0.00
0.76
FALSE
1
GTEx
Prostate
FIGNL1
0.52
0.29
enet
13
0.40
2.6e-11
-6.8
-5.1
2.9e-07
-0.29
0.05
0.95
FALSE