Best TWAS P=9.08e-11 · Best GWAS P=2.28e-13 conditioned to 6.27e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 6.5 | 6.5 | 9.1e-11 | 0.06 | 0.60 | 0.40 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -7.1 | -6.3 | 3.9e-10 | 0.95 | 0.01 | 0.99 | TRUE |