[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr2:23,453,834-25,040,082

Best TWAS P=5.27e-11 · Best GWAS P=3.05e-14 conditioned to 0.000389

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex UBXN2A 0.22 0.18 enet 28 0.24 3.0e-28 -7.1 6.5 6.2e-11 -0.61 0.06 0.94 FALSE
2 GTEx Cells EBV-transformed lymphocytes PFN4 0.18 0.13 lasso 12 0.12 8.9e-05 -4.5 -5.8 6.4e-09 0.61 0.24 0.31 FALSE
3 GTEx Colon Transverse UBXN2A 0.11 0.01 enet 8 0.03 8.7e-03 -5.0 -5.1 3.1e-07 0.18 0.21 0.16 FALSE
4 GTEx Esophagus Gastroesophageal Junction PFN4 0.13 0.01 lasso 12 0.01 9.7e-02 -5.9 -5.7 1.5e-08 0.54 0.08 0.34 FALSE
5 GTEx Esophagus Mucosa TP53I3 0.16 0.03 enet 23 0.06 8.2e-05 2.0 -5.6 2.1e-08 0.29 0.11 0.10 FALSE
6 GTEx Heart Atrial Appendage UBXN2A 0.08 0.02 lasso 3 0.02 5.2e-02 -6.3 -6.5 8.8e-11 0.56 0.18 0.46 FALSE
7 GTEx Heart Atrial Appendage PFN4 0.22 0.06 lasso 7 0.10 2.8e-05 2.0 -5.9 3.0e-09 0.64 0.05 0.93 FALSE
8 GTEx Heart Left Ventricle PFN4 0.23 0.28 lasso 6 0.28 4.1e-15 -4.5 -5.7 1.5e-08 0.62 0.97 0.03 FALSE
9 GTEx Spleen UBXN2A 0.31 0.11 enet 19 0.17 4.1e-05 6.3 -6.1 1.1e-09 0.41 0.32 0.33 TRUE
10 METSIM Adipose UBXN2A 0.07 0.03 bslmm 403 0.06 5.3e-10 -5.0 -5.3 1.3e-07 0.40 0.22 0.78 FALSE
11 ROSMAP Brain Pre-frontal Cortex UBXN2A 0.03 0.01 lasso 4 0.02 2.2e-03 -6.2 6.6 5.3e-11 -0.52 0.21 0.41 TRUE
12 The Cancer Genome Atlas Brain Lower Grade Glioma UBXN2A 0.04 0.04 lasso 1 0.03 1.4e-04 -6.2 6.2 5.2e-10 -0.57 0.16 0.62 FALSE