Best TWAS P=1e-10 · Best GWAS P=1.05e-13 conditioned to 1.48e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | TMEM161B-AS1 | 0.19 | 0.09 | lasso | 6 | 0.09 | 4.2e-04 | 3.6 | 5.3 | 1.1e-07 | -0.29 | 0.30 | 0.09 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 6.5 | 6.5 | 1.0e-10 | 0.06 | 0.73 | 0.27 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -7.2 | -6.3 | 3.2e-10 | 0.95 | 0.01 | 0.99 | TRUE |