[Hub]/) : Traits : Arm fat percentage (right) :

chr11:130,025,387-131,476,599

Best TWAS P=2.55e-15 · Best GWAS P=2.5e-13 conditioned to 0.0072

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SNX19 0.21 0.21 lasso 6 0.22 6.7e-26 6.2 -6.0 2.7e-09 0.49 0.93 0.07 FALSE
2 GTEx Adipose Subcutaneous SNX19 0.21 0.15 enet 24 0.16 2.3e-13 6.4 -7.1 1.0e-12 0.73 0.36 0.64 FALSE
3 GTEx Adipose Visceral Omentum SNX19 0.22 0.10 lasso 7 0.10 8.0e-06 6.4 -7.0 2.0e-12 0.63 0.14 0.85 FALSE
4 GTEx Adrenal Gland SNX19 0.24 0.16 lasso 4 0.06 3.2e-03 6.2 -7.0 3.2e-12 0.58 0.15 0.84 FALSE
5 GTEx Artery Aorta SNX19 0.39 0.15 lasso 6 0.28 1.1e-15 6.0 -5.9 3.0e-09 0.54 0.08 0.92 FALSE
6 GTEx Artery Aorta RP11-890B15.3 0.19 0.01 enet 1 0.00 4.8e-01 6.0 -6.0 2.6e-09 0.50 0.06 0.32 FALSE
7 GTEx Artery Coronary SNX19 0.25 0.16 lasso 11 0.18 1.4e-06 6.3 -6.1 8.8e-10 0.55 0.46 0.46 FALSE
8 GTEx Artery Tibial SNX19 0.22 0.14 lasso 6 0.20 1.5e-15 -3.4 -6.1 1.2e-09 0.57 0.15 0.85 FALSE
9 GTEx Brain Caudate basal ganglia SNX19 0.33 0.12 lasso 5 0.12 2.8e-04 6.3 -7.3 3.4e-13 0.57 0.08 0.85 FALSE
10 GTEx Brain Cerebellar Hemisphere SNX19 0.33 0.23 lasso 7 0.28 7.2e-08 -2.8 -5.3 1.3e-07 0.49 0.10 0.83 FALSE
11 GTEx Brain Cortex SNX19 0.36 0.12 lasso 7 0.16 3.3e-05 6.0 -6.8 8.5e-12 0.53 0.05 0.91 FALSE
12 GTEx Brain Frontal Cortex BA9 SNX19 0.41 0.20 lasso 7 0.37 7.1e-11 -6.6 -7.2 4.4e-13 0.52 0.06 0.92 FALSE
13 GTEx Brain Hippocampus SNX19 0.24 0.07 enet 17 0.16 1.8e-04 -6.6 -7.0 3.8e-12 0.49 0.07 0.76 FALSE
14 GTEx Brain Hypothalamus SNX19 0.32 0.04 lasso 5 0.13 7.4e-04 6.7 -7.9 2.6e-15 0.67 0.07 0.87 TRUE
15 GTEx Brain Nucleus accumbens basal ganglia RP11-890B15.3 0.46 0.16 lasso 7 0.04 3.9e-02 -5.5 -5.8 6.9e-09 0.36 0.10 0.15 FALSE
16 GTEx Brain Putamen basal ganglia SNX19 0.35 -0.01 enet 18 0.02 1.4e-01 -2.4 -6.0 2.0e-09 0.30 0.06 0.39 FALSE
17 GTEx Breast Mammary Tissue (Female) RP11-890B15.3 0.17 0.01 lasso 4 0.02 1.0e-01 5.9 -5.7 1.2e-08 0.56 0.06 0.18 FALSE
18 GTEx Cells EBV-transformed lymphocytes SNX19 0.29 0.28 lasso 2 0.26 5.1e-09 6.4 -6.4 1.6e-10 0.55 0.67 0.32 FALSE
19 GTEx Colon Sigmoid SNX19 0.34 0.10 lasso 7 0.28 2.2e-10 6.3 -5.7 1.2e-08 0.49 0.50 0.50 FALSE
20 GTEx Colon Transverse SNX19 0.40 0.29 enet 19 0.38 4.2e-19 -3.4 -5.3 8.7e-08 0.54 0.99 0.01 FALSE
21 GTEx Esophagus Gastroesophageal Junction SNX19 0.35 0.07 enet 29 0.22 1.7e-08 6.4 -5.8 6.4e-09 0.70 0.11 0.88 FALSE
22 GTEx Esophagus Muscularis SNX19 0.31 0.18 enet 23 0.25 1.2e-15 6.2 -7.3 3.8e-13 0.76 0.07 0.93 FALSE
23 GTEx Heart Atrial Appendage SNX19 0.50 0.20 enet 32 0.32 4.9e-15 -7.1 -7.3 2.1e-13 0.83 0.02 0.98 FALSE
24 GTEx Heart Left Ventricle SNX19 0.21 0.06 lasso 4 0.05 9.7e-04 6.4 -7.1 1.2e-12 0.59 0.08 0.89 FALSE
25 GTEx Muscle Skeletal SNX19 0.27 0.23 lasso 5 0.26 2.5e-25 -3.7 -5.5 3.6e-08 0.43 1.00 0.00 FALSE
26 GTEx Pancreas SNX19 0.35 0.12 enet 19 0.27 1.2e-11 6.4 -6.3 2.1e-10 0.63 0.08 0.92 FALSE
27 GTEx Pancreas RP11-890B15.3 0.16 0.02 lasso 2 0.01 1.9e-01 -7.2 -7.3 3.2e-13 0.60 0.04 0.88 FALSE
28 GTEx Skin Not Sun Exposed Suprapubic RP11-890B15.3 0.22 0.13 enet 16 0.21 9.0e-12 -3.4 -6.0 2.3e-09 0.49 0.95 0.04 FALSE
29 GTEx Stomach SNX19 0.39 0.29 lasso 13 0.27 2.0e-13 6.3 -7.3 3.6e-13 0.70 0.46 0.54 FALSE
30 GTEx Testis SNX19 0.59 0.25 enet 24 0.38 7.1e-18 -7.2 -7.2 6.2e-13 0.68 0.02 0.98 FALSE
31 METSIM Adipose RP11-890B15.3 0.12 0.12 lasso 5 0.12 9.4e-17 6.2 -6.2 4.6e-10 0.48 0.74 0.26 FALSE
32 METSIM Adipose SNX19 0.16 0.20 lasso 2 0.20 1.5e-28 6.2 -6.1 1.2e-09 0.54 0.92 0.08 FALSE
33 NTR Blood SNX19 0.06 0.05 lasso 6 0.06 9.9e-19 -3.5 -6.1 1.2e-09 0.53 0.99 0.01 FALSE
34 ROSMAP Brain Pre-frontal Cortex SNX19 0.41 0.49 lasso 6 0.51 2.7e-75 6.2 -7.2 5.8e-13 0.61 0.93 0.07 FALSE
35 The Cancer Genome Atlas Esophageal Carcinoma SNX19 0.15 0.08 lasso 6 0.12 1.4e-04 6.2 -7.2 8.3e-13 0.66 0.17 0.60 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SNX19 0.11 0.19 enet 15 0.24 3.2e-26 6.2 -6.9 5.3e-12 0.61 0.86 0.14 FALSE
37 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SNX19 0.11 0.08 lasso 6 0.12 3.4e-07 -3.6 -5.2 2.7e-07 0.42 0.98 0.00 FALSE
38 The Cancer Genome Atlas Brain Lower Grade Glioma SNX19 0.17 0.20 lasso 6 0.23 9.8e-26 6.2 -6.7 1.6e-11 0.61 0.80 0.20 FALSE
39 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SNX19 0.12 0.05 blup 98 0.07 3.0e-04 -3.7 -6.3 2.3e-10 0.49 0.21 0.35 FALSE
40 The Cancer Genome Atlas Pancreatic Adenocarcinoma SNX19 0.06 0.04 blup 100 0.06 1.3e-03 5.9 -7.4 1.8e-13 0.76 0.06 0.42 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma SNX19 0.24 0.23 lasso 8 0.32 2.6e-32 -3.7 -5.9 3.9e-09 0.52 0.99 0.01 FALSE