Best TWAS P=1.33e-08 · Best GWAS P=2.34e-09 conditioned to 0.0263
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | REXO1 | 0.07 | 0.01 | bslmm | 391 | 0.01 | 1.7e-02 | -3.9 | 5.6 | 2.4e-08 | -0.51 | 0.03 | 0.90 | FALSE |
| 2 | GTEx | Esophagus Muscularis | KLF16 | 0.17 | 0.07 | enet | 9 | 0.09 | 3.7e-06 | -5.6 | -5.2 | 1.9e-07 | 0.50 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Esophagus Muscularis | CTB-31O20.6 | 0.16 | 0.07 | lasso | 5 | 0.05 | 7.8e-04 | -5.6 | -5.7 | 1.5e-08 | 0.50 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ATP8B3 | 0.04 | 0.01 | blup | 49 | 0.02 | 2.2e-03 | -6.0 | -5.7 | 1.3e-08 | 0.84 | 0.00 | 0.66 | TRUE |