TWAS
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Traits
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Traits
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Arm fat percentage (right)
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chr19:1,127,720-2,560,423
Best TWAS P=1.33e-08 · Best GWAS P=2.34e-09 conditioned to 0.0263
1.2M
1.4M
1.6M
1.8M
2M
2.2M
2.4M
2.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
ATP8B3
0.04
0.01
blup
49
0.02
2.2e-03
-6.0
-5.7
1.3e-08
0.84
0.00
0.66
TRUE
3
GTEx
Esophagus Muscularis
CTB-31O20.6
0.16
0.07
lasso
5
0.05
7.8e-04
-5.6
-5.7
1.5e-08
0.50
0.02
0.96
FALSE
1
CommonMind
Brain Pre-frontal Cortex
REXO1
0.07
0.01
bslmm
391
0.01
1.7e-02
-3.9
5.6
2.4e-08
-0.51
0.03
0.90
FALSE
2
GTEx
Esophagus Muscularis
KLF16
0.17
0.07
enet
9
0.09
3.7e-06
-5.6
-5.2
1.9e-07
0.50
0.02
0.97
FALSE