Best TWAS P=2.57e-08 · Best GWAS P=5.98e-07 conditioned to 0.398
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CNOT6L | 0.23 | 0.24 | lasso | 9 | 0.26 | 5.5e-20 | 5.0 | -5.6 | 2.6e-08 | -0.95 | 0.02 | 0.97 | TRUE |
| 2 | GTEx | Esophagus Muscularis | CNOT6L | 0.18 | 0.19 | lasso | 11 | 0.19 | 1.3e-11 | 4.9 | -5.2 | 2.5e-07 | -0.97 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Nerve Tibial | CNOT6L | 0.19 | 0.14 | enet | 28 | 0.14 | 2.7e-10 | 4.7 | -5.5 | 4.5e-08 | -0.75 | 0.05 | 0.94 | FALSE |