Best TWAS P=1.52e-07 · Best GWAS P=1.93e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | METTL10 | 0.11 | 0.06 | enet | 6 | 0.05 | 1.7e-04 | -5.1 | -5.2 | 1.7e-07 | 0.96 | 0.02 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | METTL10 | 0.10 | 0.14 | blup | 43 | 0.14 | 7.4e-16 | -5.2 | -5.3 | 1.5e-07 | 0.98 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | METTL10 | 0.11 | 0.19 | lasso | 6 | 0.19 | 7.3e-22 | -5.0 | -5.1 | 2.7e-07 | 1.00 | 0.01 | 0.99 | FALSE |