[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr19:3,652,410-5,153,606

Best TWAS P=5.79e-13 · Best GWAS P=2.94e-10 conditioned to 0.158

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	UBXN6	0.27	0.25	enet	28	0.29	4.6e-36	5.7	-6.5	6.1e-11	-0.88	0.04	0.96	FALSE
2	GTEx	Adipose Subcutaneous	CTB-50L17.9	0.29	0.30	lasso	2	0.30	2.3e-24	5.8	-5.7	9.4e-09	-0.90	0.07	0.93	FALSE
3	GTEx	Adipose Visceral Omentum	CHAF1A	0.24	0.26	lasso	3	0.26	6.2e-14	6.1	-5.9	3.0e-09	-0.94	0.00	1.00	FALSE
4	GTEx	Adipose Visceral Omentum	CTB-50L17.9	0.30	0.23	lasso	4	0.22	2.1e-11	5.8	-5.9	4.2e-09	-0.87	0.04	0.96	FALSE
5	GTEx	Adrenal Gland	CHAF1A	0.22	0.18	lasso	3	0.17	1.1e-06	5.6	-5.9	3.8e-09	-0.93	0.01	0.98	FALSE
6	GTEx	Adrenal Gland	CTB-50L17.9	0.38	0.35	lasso	3	0.34	5.8e-13	5.8	-5.8	9.2e-09	-0.90	0.06	0.94	FALSE
7	GTEx	Adrenal Gland	AC007292.6	0.24	0.14	lasso	4	0.07	2.0e-03	5.7	-5.4	6.7e-08	-0.88	0.04	0.86	FALSE
8	GTEx	Artery Aorta	MPND	0.14	0.06	lasso	2	0.03	6.7e-03	5.6	5.6	2.2e-08	0.88	0.04	0.84	FALSE
9	GTEx	Artery Aorta	CHAF1A	0.29	0.33	lasso	3	0.34	2.4e-19	6.1	-5.7	1.1e-08	-0.94	0.01	0.99	FALSE
10	GTEx	Artery Aorta	UBXN6	0.13	0.02	lasso	5	0.03	5.7e-03	-5.7	-7.0	2.6e-12	-0.82	0.02	0.96	FALSE
11	GTEx	Artery Aorta	CTB-50L17.5	0.16	0.15	lasso	7	0.15	1.0e-08	6.3	-6.2	4.5e-10	-0.99	0.00	1.00	FALSE
12	GTEx	Artery Aorta	CTB-50L17.9	0.32	0.31	lasso	4	0.30	2.9e-17	5.8	-5.9	4.4e-09	-0.90	0.06	0.94	FALSE
13	GTEx	Artery Coronary	CTB-50L17.9	0.43	0.14	lasso	6	0.12	6.5e-05	5.8	-6.2	6.0e-10	-0.81	0.03	0.88	FALSE
14	GTEx	Artery Tibial	CHAF1A	0.39	0.37	lasso	7	0.39	1.2e-32	6.1	-5.5	3.2e-08	-0.94	0.01	0.99	FALSE
15	GTEx	Artery Tibial	UBXN6	0.18	0.07	lasso	3	0.14	6.3e-11	6.3	-6.9	4.5e-12	-0.80	0.01	0.99	FALSE
16	GTEx	Artery Tibial	CTB-50L17.5	0.23	0.13	lasso	4	0.11	4.1e-09	6.3	-5.5	3.1e-08	-0.97	0.00	1.00	FALSE
17	GTEx	Artery Tibial	CTB-50L17.9	0.27	0.31	lasso	3	0.31	2.2e-24	5.8	-5.8	6.1e-09	-0.90	0.07	0.93	FALSE
18	GTEx	Artery Tibial	AC007292.6	0.13	0.07	lasso	2	0.06	3.4e-05	5.8	-5.2	2.3e-07	-0.87	0.06	0.89	FALSE
19	GTEx	Brain Caudate basal ganglia	CTB-50L17.9	0.27	0.25	lasso	2	0.24	1.8e-07	6.3	-6.3	2.6e-10	-0.98	0.00	0.99	FALSE
20	GTEx	Brain Cerebellar Hemisphere	CHAF1A	0.62	0.40	lasso	8	0.36	3.5e-10	6.3	-6.2	4.0e-10	-1.00	0.00	1.00	FALSE
21	GTEx	Brain Cerebellar Hemisphere	CTB-50L17.9	0.61	0.45	lasso	2	0.50	1.2e-14	5.8	-5.8	5.7e-09	-0.90	0.01	0.99	FALSE
22	GTEx	Brain Cerebellum	CHAF1A	0.51	0.35	lasso	4	0.34	9.7e-11	6.3	-6.2	4.2e-10	-0.99	0.01	0.99	FALSE
23	GTEx	Brain Cerebellum	CTB-50L17.5	0.33	0.22	lasso	4	0.20	1.8e-06	5.8	-5.8	6.8e-09	-0.90	0.01	0.98	FALSE
24	GTEx	Brain Cerebellum	CTB-50L17.9	0.53	0.41	lasso	2	0.50	3.6e-17	5.8	-6.4	1.7e-10	-0.90	0.01	0.99	FALSE
25	GTEx	Brain Cortex	CTB-50L17.9	0.28	0.25	lasso	2	0.25	1.7e-07	5.8	-5.8	6.4e-09	-0.90	0.02	0.97	FALSE
26	GTEx	Brain Frontal Cortex BA9	UBXN6	0.31	0.06	enet	5	0.12	3.5e-04	5.8	-6.0	1.8e-09	-0.88	0.01	0.93	FALSE
27	GTEx	Brain Frontal Cortex BA9	CTB-50L17.9	0.27	0.21	lasso	3	0.19	7.9e-06	5.8	-6.3	3.0e-10	-0.90	0.01	0.98	FALSE
28	GTEx	Brain Hypothalamus	CTB-50L17.9	0.44	0.26	lasso	4	0.24	2.8e-06	5.8	-5.6	1.8e-08	-0.89	0.02	0.90	FALSE
29	GTEx	Brain Nucleus accumbens basal ganglia	CHAF1A	0.31	0.28	lasso	2	0.24	4.0e-07	6.1	-6.1	9.6e-10	-0.95	0.01	0.99	FALSE
30	GTEx	Brain Nucleus accumbens basal ganglia	CTB-50L17.9	0.45	0.25	lasso	8	0.23	8.6e-07	6.3	-7.0	3.1e-12	-0.90	0.01	0.99	FALSE
31	GTEx	Brain Putamen basal ganglia	CHAF1A	0.40	0.34	lasso	4	0.37	1.2e-09	6.3	-5.8	9.1e-09	-0.97	0.00	0.99	FALSE
32	GTEx	Brain Putamen basal ganglia	CTB-50L17.9	0.33	0.32	lasso	1	0.33	1.2e-08	5.8	-5.8	8.2e-09	-0.90	0.01	0.98	FALSE
33	GTEx	Breast Mammary Tissue	CHAF1A	0.39	0.25	enet	25	0.26	7.1e-14	5.8	-5.2	2.3e-07	-0.87	0.02	0.98	FALSE
34	GTEx	Breast Mammary Tissue	CTB-50L17.9	0.42	0.33	lasso	9	0.32	3.0e-17	5.8	-5.8	5.4e-09	-0.90	0.06	0.94	FALSE
35	GTEx	Breast Mammary Tissue (Male)	CHAF1A	0.20	-0.01	lasso	12	0.00	4.2e-01	5.7	-5.6	2.2e-08	-0.87	0.02	0.67	FALSE
36	GTEx	Breast Mammary Tissue (Male)	CTB-50L17.9	0.30	0.18	lasso	4	0.10	2.3e-03	5.8	-5.7	9.5e-09	-0.89	0.02	0.65	FALSE
37	GTEx	Breast Mammary Tissue (Female)	CHAF1A	0.33	0.14	lasso	6	0.09	1.6e-03	6.1	-5.9	3.1e-09	-0.94	0.01	0.96	FALSE
38	GTEx	Breast Mammary Tissue (Female)	CTB-50L17.9	0.45	0.25	lasso	7	0.26	1.6e-08	5.8	-5.6	2.6e-08	-0.87	0.02	0.98	FALSE
39	GTEx	Cells EBV-transformed lymphocytes	CTB-50L17.9	0.31	0.27	lasso	1	0.23	3.6e-08	5.8	-5.8	8.2e-09	-0.90	0.04	0.95	FALSE
40	GTEx	Cells Transformed fibroblasts	UBXN6	0.09	0.10	lasso	1	0.08	1.5e-06	-5.7	-5.7	1.1e-08	-0.54	0.09	0.91	FALSE
41	GTEx	Cells Transformed fibroblasts	CTB-50L17.9	0.17	0.16	lasso	4	0.16	7.4e-12	5.8	-5.5	3.7e-08	-0.88	0.06	0.94	FALSE
42	GTEx	Colon Sigmoid	CHAF1A	0.33	0.08	lasso	5	0.12	7.5e-05	6.1	-5.7	1.5e-08	-0.91	0.01	0.99	FALSE
43	GTEx	Colon Sigmoid	UBXN6	0.34	0.15	lasso	6	0.14	1.7e-05	5.8	-6.5	1.1e-10	-0.88	0.02	0.98	FALSE
44	GTEx	Colon Sigmoid	CTB-50L17.9	0.42	0.38	lasso	5	0.37	4.4e-14	5.8	-5.8	6.1e-09	-0.90	0.02	0.98	FALSE
45	GTEx	Colon Transverse	CTB-50L17.9	0.29	0.36	lasso	2	0.38	2.3e-19	5.8	-5.2	2.4e-07	-0.87	0.07	0.93	FALSE
46	GTEx	Colon Transverse	AC007292.6	0.32	0.05	lasso	6	0.20	1.2e-09	5.6	-5.4	6.9e-08	-0.71	0.01	0.98	FALSE
47	GTEx	Esophagus Gastroesophageal Junction	CTB-50L17.9	0.22	0.18	lasso	2	0.19	1.7e-07	5.8	-5.8	5.9e-09	-0.90	0.02	0.98	FALSE
48	GTEx	Esophagus Mucosa	CTB-50L17.9	0.20	0.23	lasso	4	0.22	8.2e-15	5.8	-5.8	7.2e-09	-0.90	0.06	0.94	FALSE
49	GTEx	Esophagus Muscularis	UBXN6	0.35	0.24	enet	20	0.29	3.7e-18	5.8	-6.1	8.5e-10	-0.92	0.01	0.99	FALSE
50	GTEx	Esophagus Muscularis	CTB-50L17.5	0.28	0.17	lasso	3	0.19	6.7e-12	6.3	-5.5	4.6e-08	-0.93	0.00	1.00	FALSE
51	GTEx	Esophagus Muscularis	CTB-50L17.9	0.37	0.36	lasso	5	0.35	3.8e-22	5.8	-5.8	7.6e-09	-0.90	0.06	0.94	FALSE
52	GTEx	Esophagus Muscularis	AC007292.6	0.13	0.08	lasso	2	0.05	4.9e-04	5.7	-5.7	9.7e-09	-0.88	0.05	0.92	FALSE
53	GTEx	Heart Atrial Appendage	CHAF1A	0.28	0.19	enet	12	0.19	4.9e-09	6.1	-5.2	1.8e-07	-0.92	0.01	0.99	FALSE
54	GTEx	Heart Atrial Appendage	UBXN6	0.34	0.12	lasso	6	0.21	6.5e-10	6.3	-6.8	1.1e-11	-0.87	0.01	0.99	FALSE
55	GTEx	Heart Atrial Appendage	CTB-50L17.9	0.32	0.34	lasso	3	0.34	3.8e-16	5.8	-6.0	1.9e-09	-0.89	0.06	0.94	FALSE
56	GTEx	Heart Left Ventricle	CHAF1A	0.17	0.12	lasso	2	0.11	1.9e-06	6.3	-6.3	2.7e-10	-1.00	0.00	1.00	FALSE
57	GTEx	Heart Left Ventricle	UBXN6	0.21	0.14	lasso	6	0.16	5.6e-09	-5.8	-6.6	4.1e-11	-0.71	0.07	0.93	FALSE
58	GTEx	Heart Left Ventricle	CTB-50L17.9	0.25	0.17	lasso	2	0.18	5.4e-10	5.8	-5.4	6.1e-08	-0.87	0.04	0.96	FALSE
59	GTEx	Lung	CTB-50L17.9	0.23	0.32	lasso	2	0.32	2.4e-25	5.8	-5.8	5.4e-09	-0.89	0.06	0.94	FALSE
60	GTEx	Muscle Skeletal	MPND	0.10	0.07	lasso	3	0.05	6.3e-06	5.7	5.7	1.5e-08	0.88	0.05	0.95	FALSE
61	GTEx	Muscle Skeletal	CHAF1A	0.18	0.21	lasso	2	0.20	9.7e-20	6.3	-6.3	2.8e-10	-0.99	0.00	1.00	FALSE
62	GTEx	Muscle Skeletal	UBXN6	0.19	0.14	lasso	5	0.18	4.1e-17	-5.8	-7.0	3.1e-12	-0.82	0.06	0.94	FALSE
63	GTEx	Muscle Skeletal	CTB-50L17.9	0.23	0.23	lasso	5	0.21	2.0e-20	5.8	-5.8	5.1e-09	-0.90	0.06	0.94	FALSE
64	GTEx	Muscle Skeletal	AC007292.3	0.08	0.03	lasso	3	0.04	1.4e-04	5.7	5.5	3.4e-08	0.88	0.04	0.96	FALSE
65	GTEx	Nerve Tibial	UBXN6	0.17	0.08	enet	20	0.09	4.4e-07	5.8	-6.2	6.8e-10	-0.78	0.02	0.98	FALSE
66	GTEx	Nerve Tibial	CTB-50L17.5	0.11	0.08	enet	4	0.08	1.6e-06	6.1	-6.2	4.7e-10	-0.96	0.01	0.99	FALSE
67	GTEx	Nerve Tibial	CTB-50L17.9	0.35	0.41	lasso	1	0.40	2.1e-30	5.8	-5.8	8.2e-09	-0.90	0.07	0.93	FALSE
68	GTEx	Ovary	CTB-50L17.9	0.29	0.24	lasso	2	0.21	6.5e-06	5.8	-5.8	6.3e-09	-0.88	0.02	0.95	FALSE
69	GTEx	Pancreas	CHAF1A	0.23	0.10	enet	14	0.10	6.6e-05	6.3	-5.4	6.1e-08	-0.83	0.01	0.99	FALSE
70	GTEx	Pancreas	CTB-50L17.9	0.24	0.15	lasso	4	0.07	1.0e-03	5.8	-5.8	6.3e-09	-0.89	0.04	0.95	FALSE
71	GTEx	Prostate	UBXN6	0.27	0.15	enet	19	0.14	2.4e-04	5.8	-5.7	9.4e-09	-0.75	0.03	0.77	FALSE
72	GTEx	Skin Not Sun Exposed Suprapubic	CHAF1A	0.27	0.22	lasso	5	0.24	2.8e-13	5.8	-5.4	5.3e-08	-0.91	0.01	0.99	FALSE
73	GTEx	Skin Not Sun Exposed Suprapubic	CTB-50L17.9	0.43	0.52	lasso	2	0.51	3.3e-32	5.8	-5.8	7.3e-09	-0.90	0.06	0.94	FALSE
74	GTEx	Skin Not Sun Exposed Suprapubic	AC007292.6	0.11	0.08	lasso	6	0.07	7.8e-05	6.3	-6.1	1.3e-09	-0.92	0.01	0.98	FALSE
75	GTEx	Skin Sun Exposed Lower leg	CHAF1A	0.19	0.18	lasso	1	0.17	5.1e-14	6.1	-6.1	9.1e-10	-0.95	0.01	0.99	FALSE
76	GTEx	Skin Sun Exposed Lower leg	CTB-50L17.9	0.39	0.48	lasso	3	0.47	7.7e-44	5.8	-5.8	7.5e-09	-0.90	0.07	0.93	FALSE
77	GTEx	Small Intestine Terminal Ileum	CTB-50L17.9	0.46	0.34	lasso	4	0.36	7.2e-09	5.8	-5.7	1.6e-08	-0.89	0.02	0.97	FALSE
78	GTEx	Stomach	CTB-50L17.9	0.28	0.31	lasso	1	0.31	3.6e-15	5.8	-5.8	8.2e-09	-0.90	0.06	0.94	FALSE
79	GTEx	Stomach	AC007292.4	0.27	0.09	lasso	5	0.04	4.0e-03	-5.9	5.8	5.5e-09	0.49	0.04	0.73	FALSE
80	GTEx	Testis	CHAF1A	0.18	0.09	lasso	2	0.07	4.0e-04	6.3	-6.0	1.7e-09	-0.98	0.01	0.96	FALSE
81	GTEx	Testis	UBXN6	0.20	0.10	lasso	3	0.10	2.9e-05	5.8	-6.0	2.6e-09	-0.94	0.02	0.98	FALSE
82	GTEx	Testis	CTB-50L17.9	0.39	0.30	enet	36	0.34	9.4e-16	5.8	-6.5	1.1e-10	-0.79	0.04	0.96	FALSE
83	GTEx	Thyroid	UBXN6	0.25	0.19	lasso	5	0.23	8.8e-18	6.3	-6.3	2.8e-10	-0.92	0.01	0.99	FALSE
84	GTEx	Thyroid	CTB-50L17.9	0.35	0.42	lasso	2	0.42	2.2e-34	5.8	-5.8	8.2e-09	-0.90	0.07	0.93	FALSE
85	GTEx	Vagina	CTB-50L17.9	0.38	0.26	lasso	5	0.23	5.7e-06	6.3	-6.3	2.4e-10	-0.99	0.01	0.98	FALSE
86	GTEx	Whole Blood	CTB-50L17.9	0.21	0.17	lasso	3	0.18	9.6e-17	5.8	-5.7	9.9e-09	-0.92	0.02	0.98	FALSE
87	The Cancer Genome Atlas	Breast Invasive Carcinoma	UBXN6	0.03	0.03	lasso	3	0.03	2.3e-06	-5.7	-6.0	1.5e-09	-0.58	0.04	0.96	FALSE
88	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UBXN6	0.05	0.01	blup	57	0.04	6.6e-05	6.3	-7.2	5.8e-13	-0.74	0.00	0.99	TRUE
89	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CHAF1A	0.12	0.11	lasso	3	0.12	7.9e-13	6.1	-6.3	2.3e-10	-0.93	0.01	0.99	FALSE
90	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MPND	0.05	0.03	lasso	3	0.02	5.3e-03	6.0	6.0	2.2e-09	0.87	0.01	0.86	FALSE
91	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBXN6	0.18	0.17	enet	18	0.18	9.9e-20	6.3	-6.2	5.3e-10	-0.95	0.00	1.00	FALSE
92	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CHAF1A	0.15	0.12	lasso	2	0.12	3.2e-07	6.1	-6.2	7.4e-10	-0.95	0.01	0.99	FALSE
93	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UBXN6	0.15	0.10	lasso	1	0.10	2.8e-06	5.8	-5.8	8.2e-09	-0.90	0.01	0.98	FALSE
94	The Cancer Genome Atlas	Brain Lower Grade Glioma	CHAF1A	0.17	0.14	lasso	4	0.16	1.1e-17	6.1	-5.3	9.7e-08	-0.94	0.01	0.99	FALSE
95	The Cancer Genome Atlas	Lung Adenocarcinoma	CHAF1A	0.05	0.04	lasso	4	0.03	2.3e-04	6.3	-5.9	3.9e-09	-0.99	0.00	0.99	FALSE
96	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBXN6	0.04	0.03	lasso	2	0.02	1.6e-03	5.8	-6.2	6.2e-10	-0.97	0.00	0.94	FALSE
97	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CHAF1A	0.20	0.11	lasso	2	0.11	5.6e-05	6.3	-6.5	8.5e-11	-0.95	0.00	0.99	FALSE
98	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UBXN6	0.23	0.11	lasso	5	0.12	2.5e-05	5.8	-6.2	4.9e-10	-0.78	0.01	0.82	FALSE
99	The Cancer Genome Atlas	Prostate Adenocarcinoma	CHAF1A	0.13	0.09	lasso	6	0.10	3.5e-10	6.3	-5.5	5.1e-08	-0.96	0.00	1.00	FALSE
100	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBXN6	0.13	0.10	lasso	2	0.10	1.3e-10	6.3	-6.6	5.4e-11	-0.99	0.00	1.00	FALSE
101	The Cancer Genome Atlas	Thyroid Carcinoma	CHAF1A	0.22	0.19	lasso	3	0.20	5.4e-19	6.1	-5.5	4.1e-08	-0.95	0.00	1.00	FALSE
102	The Cancer Genome Atlas	Thyroid Carcinoma	UBXN6	0.16	0.12	lasso	2	0.12	5.4e-12	6.3	-6.5	6.4e-11	-1.00	0.00	1.00	FALSE