Best TWAS P=6.3e-09 · Best GWAS P=2.52e-08 conditioned to 8.16e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | BRD3 | 0.17 | 0.03 | enet | 14 | 0.09 | 1.5e-07 | -2.6 | -5.3 | 1.2e-07 | 0.00 | 0.70 | 0.13 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | LINC00094 | 0.14 | 0.01 | enet | 40 | 0.03 | 1.7e-03 | -3.9 | -5.3 | 1.2e-07 | -0.03 | 0.45 | 0.18 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | ABO | 0.27 | 0.31 | blup | 43 | 0.33 | 2.1e-19 | -5.0 | -5.3 | 1.4e-07 | 0.04 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ABO | 0.26 | 0.23 | enet | 10 | 0.26 | 6.0e-29 | -4.9 | -5.2 | 2.6e-07 | 0.06 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | ABO | 0.23 | 0.21 | lasso | 5 | 0.20 | 6.7e-09 | -5.1 | -5.2 | 2.5e-07 | 0.06 | 0.00 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Rectum Adenocarcinoma | ABO | 0.48 | 0.23 | enet | 10 | 0.27 | 4.7e-07 | -5.0 | -5.8 | 6.3e-09 | 0.07 | 0.00 | 0.96 | TRUE |