Best TWAS P=1.1e-12 · Best GWAS P=2.46e-54 conditioned to 1.57e-48
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | LEMD3 | 0.14 | 0.05 | lasso | 8 | 0.05 | 1.1e-03 | -4.7 | -6.2 | 5.5e-10 | 0.11 | 0.36 | 0.25 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | LEMD3 | 0.12 | 0.03 | enet | 12 | 0.06 | 7.5e-04 | -4.7 | -5.1 | 3.1e-07 | 0.11 | 0.32 | 0.08 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | RBMS1P1 | 0.17 | 0.03 | lasso | 11 | 0.04 | 7.3e-03 | 9.2 | -7.1 | 1.1e-12 | -0.40 | 0.07 | 0.40 | TRUE |
| 4 | GTEx | Nerve Tibial | LEMD3 | 0.12 | 0.14 | enet | 13 | 0.16 | 2.0e-11 | -4.5 | -5.9 | 2.9e-09 | 0.11 | 0.71 | 0.29 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | LEMD3 | 0.02 | 0.02 | blup | 36 | 0.02 | 5.9e-03 | -6.0 | -5.4 | 7.1e-08 | 0.12 | 0.01 | 0.82 | FALSE |