Best TWAS P=2.58e-08 · Best GWAS P=1.49e-06 conditioned to 0.277
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Colon Adenocarcinoma | ZNF470 | 0.05 | 0.02 | blup | 73 | 0.04 | 0.00307 | -4.2 | 5.2 | 1.6e-07 | -0.78 | 0.01 | 0.57 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ZNF470 | 0.06 | 0.02 | blup | 72 | 0.03 | 0.00018 | -4.6 | 5.3 | 1.1e-07 | -0.76 | 0.01 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Stomach Adenocarcinoma | ZNF71 | 0.07 | 0.05 | blup | 78 | 0.02 | 0.01560 | -4.2 | 5.6 | 2.6e-08 | -0.73 | 0.00 | 0.88 | TRUE |