Best TWAS P=1.12e-08 · Best GWAS P=5.22e-07 conditioned to 0.321
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | FHL3 | 0.24 | 0.15 | enet | 17 | 0.34 | 7.4e-13 | 4.5 | 5.6 | 1.9e-08 | -0.79 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Artery Aorta | FHL3 | 0.35 | 0.22 | lasso | 4 | 0.27 | 3.9e-15 | 4.5 | 5.1 | 3.1e-07 | -0.91 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Pancreas | FHL3 | 0.17 | 0.05 | lasso | 3 | 0.10 | 6.6e-05 | -5.0 | 5.3 | 1.5e-07 | -0.91 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | FHL3 | 0.10 | 0.05 | lasso | 2 | 0.06 | 2.9e-04 | 4.8 | 5.2 | 1.9e-07 | -0.92 | 0.00 | 0.92 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | FHL3 | 0.13 | 0.03 | enet | 6 | 0.05 | 4.9e-04 | -5.0 | 5.7 | 1.1e-08 | -0.77 | 0.00 | 0.82 | TRUE |