Best TWAS P=1.49e-09 · Best GWAS P=3.82e-09 conditioned to 0.277
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | BTD | 0.07 | 0.09 | lasso | 3 | 0.07 | 1.2e-09 | 5.7 | 5.9 | 4.8e-09 | 0.78 | 0.02 | 0.98 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | AC090945.1 | 0.10 | 0.12 | lasso | 7 | 0.11 | 2.8e-14 | 5.7 | 6.0 | 1.5e-09 | 0.89 | 0.03 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | BTD | 0.07 | 0.04 | enet | 9 | 0.04 | 1.6e-03 | -5.2 | 5.1 | 3.1e-07 | 0.51 | 0.01 | 0.48 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BTD | 0.04 | 0.02 | lasso | 3 | 0.02 | 6.5e-03 | 5.7 | 5.9 | 3.5e-09 | 0.87 | 0.01 | 0.75 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | BTD | 0.08 | 0.12 | lasso | 4 | 0.10 | 5.0e-10 | 4.9 | 5.3 | 1.0e-07 | 0.70 | 0.08 | 0.92 | FALSE |