Best TWAS P=7.28e-08 · Best GWAS P=1.61e-08 conditioned to 0.00118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | TIPARP-AS1 | 0.23 | 0.14 | enet | 18 | 0.15 | 2.0e-09 | -4.6 | 5.2 | 1.6e-07 | -0.48 | 0.51 | 0.48 | FALSE |
| 2 | GTEx | Nerve Tibial | TIPARP-AS1 | 0.09 | 0.10 | lasso | 3 | 0.10 | 1.7e-07 | -4.6 | 5.1 | 2.7e-07 | -0.43 | 0.47 | 0.48 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | TIPARP-AS1 | 0.17 | 0.16 | enet | 9 | 0.16 | 3.7e-09 | -4.6 | 5.2 | 1.9e-07 | -0.48 | 0.50 | 0.49 | FALSE |
| 4 | GTEx | Stomach | TIPARP-AS1 | 0.17 | 0.08 | enet | 7 | 0.11 | 6.4e-06 | -4.6 | 5.4 | 7.3e-08 | -0.54 | 0.11 | 0.79 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LOC100287227 | 0.09 | 0.02 | enet | 8 | 0.02 | 1.3e-03 | -4.6 | -5.2 | 2.6e-07 | 0.26 | 0.00 | 0.37 | FALSE |