Best TWAS P=2.21e-19 · Best GWAS P=4.31e-20 conditioned to 0.0407
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | TMEM161B-AS1 | 0.19 | 0.09 | lasso | 6 | 0.09 | 4.2e-04 | 3.8 | 5.8 | 7.0e-09 | 0.36 | 0.27 | 0.16 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 9.0 | 9.0 | 2.2e-19 | 0.95 | 0.00 | 1.00 | TRUE |