[Hub]/) : Traits : Arm fat mass (left) :

chr11:63,295,034-66,919,278

Best TWAS P=1.31e-11 · Best GWAS P=3.09e-11 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FIBP 0.08 0.11 enet 20 0.12 8.1e-14 -5.3 -6.5 1.0e-10 -0.34 0.81 0.19 FALSE
2 CommonMind Brain Pre-frontal Cortex SNX32 0.46 0.36 lasso 8 0.39 1.9e-50 -5.5 -5.2 1.7e-07 -0.16 0.80 0.20 FALSE
3 GTEx Adipose Subcutaneous CTSW 0.30 0.18 lasso 6 0.16 3.9e-13 -5.3 5.4 5.7e-08 0.13 0.89 0.11 FALSE
4 GTEx Adipose Visceral Omentum TRPT1 0.16 0.05 lasso 5 0.04 3.0e-03 5.0 6.1 1.3e-09 0.04 0.09 0.37 FALSE
5 GTEx Adipose Visceral Omentum CTSW 0.22 0.20 lasso 11 0.19 5.1e-10 -5.3 5.2 2.1e-07 0.15 0.89 0.11 FALSE
6 GTEx Adrenal Gland CTSW 0.13 0.08 lasso 12 0.06 3.0e-03 -5.9 6.4 1.9e-10 0.22 0.26 0.29 FALSE
7 GTEx Artery Aorta CTSW 0.29 0.26 lasso 7 0.25 3.2e-14 -5.3 5.2 1.9e-07 0.14 0.89 0.11 FALSE
8 GTEx Artery Coronary FIBP 0.13 0.01 lasso 5 0.04 1.3e-02 -5.3 -5.2 1.5e-07 -0.18 0.16 0.22 FALSE
9 GTEx Artery Tibial CTSW 0.12 0.09 enet 22 0.11 1.2e-08 -5.3 5.1 2.8e-07 0.16 0.90 0.10 FALSE
10 GTEx Brain Cerebellar Hemisphere EFEMP2 0.35 0.15 enet 5 0.09 2.2e-03 -4.2 -5.1 4.0e-07 -0.25 0.32 0.13 FALSE
11 GTEx Breast Mammary Tissue CTSW 0.25 0.19 lasso 8 0.16 1.3e-08 -5.3 5.4 6.0e-08 0.13 0.88 0.12 FALSE
12 GTEx Breast Mammary Tissue (Male) LTBP3 0.11 -0.01 enet 26 -0.01 5.8e-01 -5.6 -5.1 3.9e-07 -0.08 0.03 0.19 FALSE
13 GTEx Breast Mammary Tissue (Male) NEAT1 0.27 0.01 enet 29 0.03 6.3e-02 -5.3 -5.8 8.3e-09 -0.16 0.04 0.30 FALSE
14 GTEx Cells EBV-transformed lymphocytes FIBP 0.40 0.21 enet 26 0.29 4.3e-10 -5.3 -5.4 6.2e-08 -0.17 0.88 0.11 FALSE
15 GTEx Cells Transformed fibroblasts EFEMP2 0.06 0.06 lasso 3 0.07 7.8e-06 -5.5 -6.0 2.3e-09 -0.23 0.39 0.52 FALSE
16 GTEx Colon Transverse TRPT1 0.24 0.20 lasso 5 0.17 1.6e-08 5.4 5.2 1.6e-07 0.03 0.33 0.66 FALSE
17 GTEx Colon Transverse CTSW 0.37 0.27 lasso 8 0.26 1.5e-12 -5.3 5.7 1.3e-08 0.17 0.84 0.16 FALSE
18 GTEx Esophagus Mucosa PLCB3 0.28 0.24 lasso 6 0.23 1.1e-15 6.2 -5.9 3.4e-09 -0.03 0.00 1.00 FALSE
19 GTEx Esophagus Mucosa CTSW 0.32 0.19 lasso 6 0.17 1.3e-11 -5.3 5.2 2.3e-07 0.13 0.89 0.11 FALSE
20 GTEx Esophagus Mucosa FKBP2 0.09 0.02 enet 18 0.05 2.6e-04 -2.4 5.1 3.1e-07 0.08 0.21 0.72 FALSE
21 GTEx Esophagus Muscularis TRPT1 0.20 0.12 enet 18 0.15 2.3e-09 5.1 5.9 4.2e-09 0.04 0.24 0.76 FALSE
22 GTEx Esophagus Muscularis CTSW 0.29 0.32 lasso 5 0.32 2.9e-20 -5.3 5.2 2.2e-07 0.11 0.89 0.11 TRUE
23 GTEx Esophagus Muscularis YIF1A 0.11 0.05 enet 11 0.04 2.4e-03 -4.4 5.2 1.6e-07 0.57 0.62 0.37 TRUE
24 GTEx Esophagus Muscularis CTD-3074O7.5 0.22 0.02 enet 17 0.09 3.7e-06 3.1 -6.5 1.0e-10 -0.50 0.28 0.50 TRUE
25 GTEx Heart Atrial Appendage TRPT1 0.19 0.14 lasso 7 0.15 2.0e-07 4.9 5.3 1.3e-07 0.04 0.50 0.49 FALSE
26 GTEx Heart Atrial Appendage KLC2 0.10 0.04 lasso 8 0.09 1.1e-04 -4.6 5.3 1.0e-07 0.56 0.28 0.40 TRUE
27 GTEx Heart Left Ventricle TRPT1 0.24 0.14 lasso 7 0.17 1.3e-09 5.1 5.1 3.3e-07 0.03 0.53 0.47 FALSE
28 GTEx Heart Left Ventricle FIBP 0.12 0.09 lasso 3 0.07 9.8e-05 -5.3 -5.8 7.1e-09 -0.17 0.75 0.15 FALSE
29 GTEx Liver CTSW 0.27 0.03 lasso 13 0.02 1.0e-01 -5.3 5.9 3.2e-09 0.23 0.07 0.08 FALSE
30 GTEx Lung CTSW 0.33 0.20 lasso 8 0.21 3.2e-16 -5.3 5.2 2.5e-07 0.11 0.89 0.11 FALSE
31 GTEx Muscle Skeletal TRPT1 0.24 0.26 lasso 6 0.27 1.6e-26 4.9 5.1 3.0e-07 0.03 0.75 0.25 FALSE
32 GTEx Muscle Skeletal FIBP 0.12 0.13 enet 10 0.13 2.6e-12 -5.3 -5.2 2.0e-07 -0.17 0.89 0.11 FALSE
33 GTEx Nerve Tibial TRPT1 0.14 0.03 lasso 6 0.07 1.8e-05 5.3 5.6 2.3e-08 0.03 0.09 0.87 FALSE
34 GTEx Nerve Tibial CTSW 0.22 0.19 lasso 7 0.18 1.3e-12 -5.3 5.4 6.8e-08 0.13 0.89 0.11 FALSE
35 GTEx Pancreas TRPT1 0.10 0.05 lasso 3 0.01 7.8e-02 4.4 5.4 8.4e-08 0.06 0.02 0.75 FALSE
36 GTEx Pancreas CTSW 0.13 0.11 lasso 3 0.08 4.0e-04 -5.3 5.3 1.2e-07 0.12 0.31 0.07 FALSE
37 GTEx Prostate CTSW 0.29 0.26 lasso 8 0.26 2.9e-07 -5.3 5.4 7.4e-08 0.13 0.53 0.09 FALSE
38 GTEx Skin Not Sun Exposed Suprapubic CTSW 0.27 0.22 lasso 12 0.22 1.9e-12 -5.3 5.9 3.4e-09 0.17 0.83 0.17 FALSE
39 GTEx Skin Sun Exposed Lower leg CTSW 0.19 0.19 lasso 6 0.18 1.1e-14 -5.3 5.4 6.2e-08 0.13 0.89 0.11 FALSE
40 GTEx Spleen CTSW 0.30 0.31 lasso 2 0.26 1.9e-07 -5.3 5.3 1.4e-07 0.13 0.86 0.12 FALSE
41 GTEx Stomach CTSW 0.18 0.20 lasso 7 0.19 1.7e-09 -5.3 5.3 1.1e-07 0.13 0.89 0.11 FALSE
42 GTEx Thyroid CTSW 0.18 0.22 lasso 2 0.21 4.6e-16 -5.3 5.5 3.2e-08 0.14 0.89 0.11 FALSE
43 GTEx Uterus PACS1 0.21 -0.01 enet 21 0.05 3.6e-02 -3.8 5.2 1.6e-07 0.42 0.07 0.29 FALSE
44 METSIM Adipose FIBP 0.05 0.02 blup 344 0.02 1.0e-03 -5.3 -5.1 4.1e-07 -0.39 0.87 0.10 FALSE
45 ROSMAP Brain Pre-frontal Cortex PRDX5 0.10 0.05 lasso 6 0.08 2.8e-10 5.9 -5.5 4.6e-08 -0.03 0.01 0.99 FALSE
46 ROSMAP Brain Pre-frontal Cortex CTSW 0.06 0.03 bslmm 328 0.03 3.6e-05 -5.6 5.8 4.9e-09 0.12 0.55 0.11 FALSE
47 ROSMAP Brain Pre-frontal Cortex KCNK4 0.14 0.12 bslmm 334 0.11 3.0e-14 5.9 6.1 1.2e-09 0.06 0.00 1.00 FALSE
48 ROSMAP Brain Pre-frontal Cortex TEX40 0.25 0.23 lasso 3 0.23 2.5e-29 6.3 -6.2 5.9e-10 -0.05 0.00 1.00 TRUE
49 ROSMAP Brain Pre-frontal Cortex RP11-783K16.10 0.07 0.05 lasso 6 0.06 9.6e-08 6.3 -6.1 1.0e-09 -0.05 0.00 1.00 FALSE
50 YFS Blood CTSW 0.53 0.41 blup 344 0.42 5.5e-149 -5.3 5.2 1.6e-07 0.08 0.89 0.11 FALSE
51 YFS Blood PRDX5 0.51 0.40 lasso 9 0.43 4.0e-157 5.9 5.7 1.2e-08 0.04 0.02 0.98 FALSE
52 TCGA Breast Tumor CTSW 0.39 0.24 lasso 15 0.19 4.2e-05 -5.3 5.5 4.5e-08 0.13 0.75 0.11 FALSE
53 TCGA Breast Tumor PACS1 0.32 0.02 lasso 3 0.12 9.5e-04 4.4 5.7 1.3e-08 0.69 0.10 0.38 TRUE
54 TCGA Breast Tumor SNX32 0.24 0.00 blup 338 0.13 7.1e-04 -5.3 -6.8 1.3e-11 -0.58 0.04 0.72 TRUE
55 TCGA Breast Normal CTSW 0.18 0.21 lasso 5 0.21 4.6e-55 -5.3 5.8 7.1e-09 0.16 0.90 0.10 FALSE
56 TCGA Breast Normal PACS1 0.02 0.01 blup 369 0.01 7.0e-05 -4.6 5.1 2.9e-07 0.38 0.17 0.09 FALSE
57 TCGA Ovarian Tumor CTSW 0.10 0.09 lasso 5 0.08 1.6e-08 -5.3 5.5 4.1e-08 0.13 0.84 0.16 FALSE
58 TCGA Prostate Tumor C11orf20 0.06 0.04 lasso 5 0.02 1.5e-03 6.2 -6.1 1.3e-09 -0.04 0.00 0.99 FALSE
59 TCGA Prostate Tumor CTSW 0.33 0.38 lasso 8 0.39 3.0e-52 -5.3 5.3 1.3e-07 0.13 0.89 0.11 FALSE
60 TCGA Prostate Tumor KCNK7 0.07 0.06 enet 16 0.05 1.6e-07 -3.9 5.9 4.4e-09 0.03 0.26 0.14 FALSE